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J Endod:富含血小板纤维蛋白的改良血运再生技术促使成熟牙髓坏死牙齿再生牙髓感觉的评估:一项临床研究

2018-09-16 lishiting MedSci原创

这篇研究的目的是通过诱导根尖血运形成以及使用富含血小板的纤维蛋白(PRF)形成一种改良的牙髓再生技术,并评估其促使成熟牙髓坏死牙齿再获牙髓感觉的可能性。

这篇研究的目的是通过诱导根尖血运形成以及使用富含血小板的纤维蛋白(PRF)形成一种改良的牙髓再生技术,并评估其促使成熟牙髓坏死牙齿再获牙髓感觉的可能性。

研究纳入了15名罹患有症状或无症状根尖周炎的牙髓坏死患者。第一次就诊时,麻醉患牙并建立开髓通道。根管的机械预备使用标准技术预备至#60-80号K锉直至根尖。使用双抗糊剂作为根管内封药,窝洞使用玻璃离子粘固剂进行暂时封闭。3周后,通过诱导出血实施牙髓再生手术,并且将新鲜预备好的PRF膜置于根管内。将White MTA直接置于PRF膜上,牙齿使用玻璃离子粘固剂垫底,复合树脂充填修复。每3个月随访直至12个月,记录电活力测试反应结果,观察实施治疗的牙齿是否再有感觉。使用卡方检验将不同时间的读数作为分类定性数据进行比较,并使用方差分析对其平均值和标准差进行比较。

结果显示,牙齿敏感性的读数显示,随访12个月期间与治疗前存在显著性差异(P < .0001)。

结论:敏感性的存在预示着已形成了具有活力的牙髓样组织。然而,通过牙髓再生治疗是否能够恢复真实的牙髓组织还存在争议,还需要大规模的调查以获得高水平的证据。

原始出处:

Nageh M, Ahmed GM, et al. Assessment of Regaining Pulp Sensibility in Mature Necrotic Teeth Using a Modified Revascularization Technique with Platelet-rich Fibrin: A Clinical Study. J Endod. 2018 Aug 30. pii: S0099-2399(18)30441-2. doi: 10.1016/j.joen.2018.06.014.

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    2019-08-21 jxrzshh
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    2018-09-18 millore
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    2018-09-18 zhouqu_8

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