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Int J Cancer:30岁以下人群肥胖也会导致结肠癌风险增加

2017-11-23 zhangfan MedSci原创

研究发现,一生中,包括30岁之前,肥胖均导致结肠癌风险增加。根据这一研究结果,应重视预防青少年超重和肥胖,防止因肥胖过度而导致早发性结肠癌

有令人信服的证据表明,成年后肥胖与结肠癌风险增加相关,但关于30岁以下人群该相关性的研究结果却是模棱两可的。

近日研究人员对PubMed 和 Web of Science数据库资料进行分析,考察39岁以下人群体重指数每增加5 kg/m2与结肠癌风险的相关性。

总计15项观察性研究纳入本次荟萃分析。研究发现BMI每增加5 kg/m2,会导致总体、男性以及女性的结肠癌风险分别增加13% (RR 1.13, 95% CI 1.08, 1.19)、17% (RR 1.17, 95% CI 1.09, 1.25)以及 8% (RR 1.08, 95% CI 1.04, 1.11),研究结果存在异质性。按肿瘤位点进行分层,BMI每增加5 kg/m2,患者结肠癌风险提高14% (RR 1.14, 95% CI 1.07, 1.22),但对于肾癌风险无显著影响(RR 1.03, 95% CI 0.95, 1.13)。

研究发现,一生中,包括30岁之前,肥胖均导致结肠癌风险增加。根据这一研究结果,应重视预防青少年超重和肥胖,防止因肥胖过度而导致早发性结肠癌。

原始出处:

Khemayanto Hidayat et al. Body fatness at an early age and risk of colorectal cancer. Obes Rev. 26 October 2017.

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    2018-01-31 sjq027
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    2017-11-26 jyzxjiangqin

    肥胖乃万病之源.

    0

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    2017-11-25 1209e435m98(暂无昵称)

    学习了.谢谢分享!

    0

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    2017-11-25 神功盖世

    学习

    0

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    2017-11-24 jihuaijun1112

    学习学习学习

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2061692, encodeId=708520616923b, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d58a435, createdName=sjq027, createdTime=Wed Jan 31 11:41:00 CST 2018, time=2018-01-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264381, encodeId=06c82643819c, content=肥胖乃万病之源., beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun Nov 26 07:25:08 CST 2017, time=2017-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264110, encodeId=c27e264110cc, content=学习了.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sat Nov 25 07:22:32 CST 2017, time=2017-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264060, encodeId=ae8326406002, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/fhZdOu27e88Voqh19n8eF8cLplo8L4nicKtH0WnE3KFELXns5XDu8rsiceK2HHDZc2SEStia5VV3Pia2QLMVqlWbHw/0, createdBy=6e012139475, createdName=神功盖世, createdTime=Sat Nov 25 01:29:38 CST 2017, time=2017-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263771, encodeId=b46b263e710a, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Fri Nov 24 00:15:36 CST 2017, time=2017-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263645, encodeId=fe232636455c, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Thu Nov 23 15:26:55 CST 2017, time=2017-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263595, encodeId=539226359509, content=这一篇文章是internationaljournalofcancer不是obesityreviews, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8c22075155, createdName=1351f0f707m, createdTime=Thu Nov 23 11:26:20 CST 2017, time=2017-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263594, encodeId=c30b263594e2, content=好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Thu Nov 23 11:02:19 CST 2017, time=2017-11-23, status=1, ipAttribution=)]
    2017-11-23 三生有幸9135

    学习一下谢谢分享

    0

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    2017-11-23 1351f0f707m

    这一篇文章是internationaljournalofcancer不是obesityreviews

    0

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    2017-11-23 smartxiuxiu

    好!

    0

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