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钟化发布用于识别COVID-19奥密克戎(BA.1)和“隐匿性”奥密克戎(BA.2)变异株的新款PCR检测试剂盒

2022-04-18 网络 网络

3月31日,株式会社钟化(Kaneka Corporation,总部:东京都港区;社长:田中稔)发布一款能同时检出COVID-19奥密克戎(BA.1)、“隐匿性”奥密克戎(BA

3月31日,株式会社钟化(Kaneka Corporation,总部:东京都港区;社长:田中稔)发布一款能同时检出COVID-19奥密克戎(BA.1)、“隐匿性”奥密克戎(BA.2)和德尔塔变异株的实时PCR检测试剂盒——钟化 RT-PCR Kit “SARS-CoV-2 (Omicron/Delta) ver.2”。该试剂盒的建议零售价为12.1万日元(含税,供100次检测)。

该检测试剂盒所使用的专有试剂是采用钟化分子检测相关技术开发的,通过单次PCR检测可检出三种变异株的存在。预计这将有助于减轻检测带来的负担,并帮助在临床环境中针对每种变异株选用最合适的药物和治疗方法。

钟化已发布下列三款产品:钟化Direct RT-PCR Kit SARS-CoV-2(一种采用钟化独创样本处理技术的体外诊断试剂,不到一小时即可出具检测结果)、能同时检出四种变异株的钟化 RT-PCR Kit “SARS-CoV-2 (L452R/E484Q/E484K/N501Y)”,以及能检出COVID-19德尔塔和奥密克戎变异株的钟化RT-PCR Kit “SARS-CoV-2 (Omicron/Delta)”。上述钟化产品正用于重大体育赛事和旅行前PCR检测,以及医疗机构和检测中心。这些产品可实现大量样本的快检。

钟化正采取广泛的措施来抗击新冠疫情。其中包括成立“感染应对行动组”(Infection Initiative Team),负责研发包括COVID-19在内的感染控制措施、扩大我们的PCR检测试剂盒产品线、开展DNA疫苗API和中间体的合同制造、开发抗体药物、提供PCR检测试剂和检测试剂盒,以及使用温控包装运输疫苗。

* 检出的COVID-19突变与变异株之间的关系(+:阳性,-:阴性)

 

 

E484A
(BA.1、BA.2的特征)

N856K
(BA.1的特征)

L452R
(德尔塔的特征)

 

定性

+

+

-

==>

BA.1

+

-

-

==>

BA.2

-

-

+

==>

德尔塔

以上代表病毒棘蛋白的氨基酸突变。按突变进行命名。E484A突变是棘蛋白从E(谷氨酰胺酸)突变为A(丙氨酸)。N856K突变是从N(天冬酰胺)突变为K(赖氨酸)。L452R突变是从L(赖氨酸)突变为R(精氨酸)。

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    2022-12-13 tastas
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  6. [GetPortalCommentsPageByObjectIdResponse(id=1991106, encodeId=661219911067b, content=<a href='/topic/show?id=69bd91e371a' target=_blank style='color:#2F92EE;'>#试剂盒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91737, encryptionId=69bd91e371a, topicName=试剂盒)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=47c5349, createdName=tastas, createdTime=Tue Dec 13 06:34:53 CST 2022, time=2022-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1936119, encodeId=3a3e193611943, content=<a href='/topic/show?id=1908984822d' target=_blank style='color:#2F92EE;'>#隐匿性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98482, encryptionId=1908984822d, topicName=隐匿性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b71f2500114, createdName=1179102698_36768926, createdTime=Thu Apr 21 19:34:53 CST 2022, time=2022-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1992636, encodeId=b339199263650, content=<a href='/topic/show?id=b9f562561a1' target=_blank style='color:#2F92EE;'>#检测试剂盒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62561, encryptionId=b9f562561a1, topicName=检测试剂盒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18b32500069, createdName=108807375_62823127, createdTime=Tue Aug 30 20:34:53 CST 2022, time=2022-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1934669, encodeId=a49e193466942, content=<a href='/topic/show?id=325762560c5' target=_blank style='color:#2F92EE;'>#检测试剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62560, encryptionId=325762560c5, topicName=检测试剂)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e572480, createdName=旅苦化文_208, createdTime=Wed Aug 03 16:34:53 CST 2022, time=2022-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1343021, encodeId=4fa4134302146, content=<a href='/topic/show?id=34cb381023e' target=_blank style='color:#2F92EE;'>#变异#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38102, encryptionId=34cb381023e, topicName=变异)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=78c32500188, createdName=12498dabm77暂无昵称, createdTime=Wed Apr 20 05:34:53 CST 2022, time=2022-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1419461, encodeId=cf9d14194614a, content=<a href='/topic/show?id=e290138682e' target=_blank style='color:#2F92EE;'>#PCR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13868, encryptionId=e290138682e, topicName=PCR)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9cc43496966, createdName=Tommy1950, createdTime=Wed Apr 20 05:34:53 CST 2022, time=2022-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1585361, encodeId=e95915853612a, content=<a href='/topic/show?id=7b31138e2ee' target=_blank style='color:#2F92EE;'>#PCR检测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13872, encryptionId=7b31138e2ee, topicName=PCR检测)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3bf517165269, createdName=howi, createdTime=Wed Apr 20 05:34:53 CST 2022, time=2022-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1618485, encodeId=bca31618485e4, content=<a href='/topic/show?id=5dbc98480ef' target=_blank style='color:#2F92EE;'>#隐匿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98480, encryptionId=5dbc98480ef, topicName=隐匿)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1caf19894563, createdName=41514493@qq.com, createdTime=Wed Apr 20 05:34:53 CST 2022, time=2022-04-20, status=1, ipAttribution=)]
    2022-04-20 Tommy1950
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    2022-04-20 howi
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