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Radiology:青少年剥脱性骨软骨炎会引起病变表层软骨发生质的改变吗?

2018-07-19 shaosai MedSci原创

本研究旨在验证是否T2 mapping序列能够发现青少年剥脱性骨软骨炎(JOCD)中股骨内侧髁病变处表层软骨组成及细微结构的早期改变,并将结果发表在Radiology上。

本研究旨在验证是否T2 mapping序列能够发现青少年剥脱性骨软骨炎(JOCD)中股骨内侧髁病变处表层软骨组成及细微结构的早期改变,并将结果发表在Radiology上。

本研究回顾性分析了16例有股骨内侧髁JOCD病变患者和18名年龄、性别和骨骼发育匹配的健康志愿者的矢状位T2 mapping序列。测量JOCD患者股骨内侧髁JOCD病变处软骨、表层软骨以及JOCD患者、健康志愿者股骨内侧髁承重区域软骨T2值。利用Wilcoxon符号等级检验和Wilcoxon等级和检验比较T2值。

结果为,在JOCD患者中,JOCD病变处软骨的T2值要显着高于JOCD病变表层的软骨T2值(P < .001)。然而,在JOCD病变表层的软骨T2值与JOCD患者股骨内侧髁承重处软骨的T2值间(P = .67)及JOCD患者股骨内侧髁承重处软骨的T2值与健康志愿者股骨内侧髁承重处软骨的T2值间(P = .30)无显着性差异。

本研究表明,在JOCD病变表层软骨与正常股骨内侧髁软骨T2之间无显着性量的差异,这表明软骨成分和细微结构无明显变化。

原始出处:

Nguyen JC, Liu F, Blankenbaker DG . et al.Juvenile Osteochondritis Dissecans: Cartilage T2 Mapping of Stable Medial Femoral Condyle Lesions.Radiology.DOI:10.1148/radiol.2018171995

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