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Am J Cardiol:荟萃分析显示焦虑是心血管疾病的危险因素

2016-06-26 MedSci MedSci原创

焦虑是否是一系列心血管疾病的危险因素目前还不清楚。研究者的目的是确定焦虑和一系列心血管疾病的相关性。搜索MEDLINE和EMBASE中包括有无焦虑受试者的队列研究,包括焦虑,担心,创伤后应激障碍、恐怖性焦虑、急性焦虑症的受试者。研究者研究焦虑与心血管死亡率,主要心血管事件(定义为心血管死亡,卒中,冠状动脉心脏疾病和心脏衰竭复合预后),卒中,冠状动脉心脏病,心脏衰竭和房颤。研究者确定了46个队列研究

焦虑是否是一系列心血管疾病的危险因素目前还不清楚。研究者的目的是确定焦虑和一系列心血管疾病的相关性。

搜索MEDLINE和EMBASE中包括有无焦虑受试者的队列研究,包括焦虑,担心,创伤后应激障碍、恐怖性焦虑、急性焦虑症的受试者。研究者研究焦虑与心血管死亡率,主要心血管事件(定义为心血管死亡,卒中,冠状动脉心脏疾病和心脏衰竭复合预后),卒中,冠状动脉心脏病,心脏衰竭和房颤。

研究者确定了46个队列研究,包含2017276例受试者和222253例焦虑患者。焦虑与心血管死亡率风险增高显著相关(RR 1.41,CI 1.13-1.76),冠心病(RR 1.41,CI 1.23 -1.61)、卒中(RR 1.71, CI 1.18-2.50)、心力衰竭(RR 1.35, CI 1.11 -1.64)。焦虑与主要心血管事件或房颤不相关,虽然CI范围较广。恐怖性焦虑比其他焦虑症与冠状动脉心脏疾病的发生风险较高更相关,创伤后应激障碍与卒中风险增加相关。灵敏度分析结果是大致一致。

焦虑症与一系列不同的心血管事件的风险升高相关,包括卒中,冠心病,心脏衰竭,心血管死亡。这些关联是否是因果关系尚不清楚。

原始出处:


Emdin CA, Odutayo A, et al. Meta-Analysis of Anxiety as a Risk Factor for Cardiovascular Disease. Am J Cardiol. 2016 May 28.

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    2017-03-13 venlin
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    2016-06-27 flyingzyx

    心身疾病

    0

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    2016-06-27 JBY

    情感也是疾病发生的相关因素

    0

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