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BMJ:危重患者颅内压增高诊断方法研究

2019-07-27 MedSci MedSci原创

研究发现,常规项检查对颅内压增高诊断敏感性较低,CT及视神经鞘直径超声可以提高较准确的诊断

近日研究人员考察了常规项检查、CT、视神经鞘直径超声(ONSD)、经颅多普勒搏动指数(TCDPI)对危重患者颅内压增高(ICP)的诊断价值。

本次研究为系统回顾和荟萃分析,收集截至2018年9月1日的相关研究资料,涉及危重病患者体检、影像学或无创检查准确性的研究。参考标准为20mmHg或更高的ICP,采用有创ICP监测,或在手术中诊断升高的ICP。

40项研究(n=5123)。常规体格检查体征中,瞳孔扩张综合敏感度和特异性分别为28.2%和85.9%,姿势综合敏感度和特异性分别为54.3%和63.6%,格拉斯哥昏迷评分为8分或以下为75.8%和39.9%。CT结果中,基底池压迫的敏感性和特异性分别为85.9%和61.0%,中线移位的敏感性和特异性分别为80.9%和42.7%,中线移位至少10毫米的敏感性和特异性分别为20.7%和89.2%。ONSD超声的ROC(AUROC)曲线下的集合面积为0.94。使用TCD-PI进行ICP升高的表现不佳(AUROC范围从0.55到0.72)。

研究发现,常规项检查对颅内压增高诊断敏感性较低,CT及视神经鞘直径超声可以提高较准确的诊断。

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    2020-03-22 gaoxiaoe
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    2019-08-26 JBY

    常规项检查对颅内压增高诊断敏感性较低,CT及视神经鞘直径超声可以提高较准确的诊断。

    0

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    2019-07-28 liuxiaona
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    2019-07-28 liuxiaona

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