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Trizell制药宣布进行干扰素α-2b基因疗法治疗恶性胸膜间皮瘤的III期关键研究

2019-03-21 不详 网络

胸膜间皮瘤干扰素α-2bTR002
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Trizell制药公司近日宣布，它已开始对其新型基因疗法TR002（一种腺病毒介导的干扰素α2b）进行III期研究，该研究用于恶性胸膜间皮瘤（MPM）患者，这些患者经一线标准治疗后失败。干扰素是人体用于对抗癌症的天然蛋白质，TR002治疗的目的是触发干扰素的多效抗肿瘤作用，随后则使用吉西他滨进行化疗。

Trizell制药公司近日宣布，它已开始对其新型基因疗法TR002（一种腺病毒介导的干扰素α2b）进行III期研究，该研究用于恶性胸膜间皮瘤（MPM）患者，这些患者经一线标准治疗后失败。干扰素是人体用于对抗癌症的天然蛋白质，TR002治疗的目的是触发干扰素的多效抗肿瘤作用，随后则使用吉西他滨进行化疗。

恶性胸膜间皮瘤是一种侵袭性和破坏性的癌症形式，影响肺的外（胸膜）膜。这种疾病通常是通过吸入石棉纤维引起的，石棉纤维从胸腔缓慢地从肺泡到肺外表面，诱发癌症。职业或环境中的石棉与矿物纤维的暴露和MPM发展之间存在明显的关联。


原始出处：

http://www.firstwordpharma.com/node/1630604#axzz5ioDx2kLe

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    2020-01-20 lifestar

    #胸膜#

    0

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    2020-02-13 juliusluan78

    #III#

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    2019-03-23 1249884fm92暂无昵称

    #间皮瘤#

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    2019-03-23 智智灵药

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