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Cardiovasc Diabetol:代谢综合征和颅内动脉粥样硬化性卒中多发病灶之间的关系

2015-09-20 phylis 译 MedSci原创

背景:随着代谢综合症(Mets)和动脉粥样硬化性卒中的发生增加,对Mets和动脉粥样硬化临床特征之间的关系引起了研究者的兴趣。这篇研究旨在调查Mets与颅内动脉粥样硬化性卒中患者的多发病灶的关系。方法:招募第一次动脉粥样硬化性卒中住院的患者202名,进行一项基于临床的回顾性研究。对多发病灶的卒中的发生,应用logistic回归分析Mets的OR值(95%CI)或Mets的各个组成部分。结果:51%

背景:随着代谢综合症(Mets)和动脉粥样硬化性卒中的发生增加,对Mets和动脉粥样硬化临床特征之间的关系引起了研究者的兴趣。这篇研究旨在调查Mets与颅内动脉粥样硬化性卒中患者的多发病灶的关系。

方法:招募第一次动脉粥样硬化性卒中住院的患者202名,进行一项基于临床的回顾性研究。对多发病灶的卒中的发生,应用logistic回归分析Mets的OR值(95%CI)或Mets的各个组成部分。

结果:51%男性患者和38%的女性卒中患者,呈多发区域卒中。Mets是女性OR:4.3 (95 % CI:1.4-13.5)多发病灶发生的重要因素,但是男性则否。根据Mets的组成,血脂障碍是男性OR=2.0(95 % CI:1.1-3.7),女性OR=3.2(95 % CI:1.1-9.1).患者多发病灶正相关的重要因素。

结论:Mets可能是颅内动脉粥样硬化性卒中多发病灶的病理生理因素,尤其是女性患者。仍需要进一步研究证实这个结果。

原文出处:

Kotani K, Satoh-Asahara N, Nakakuki T,et al.  Association between metabolic syndrome and multiple lesions of intracranial atherothrombotic stroke: a hospital-based study. Cardiovasc Diabetol. 2015 Aug 14;14:108. doi: 10.1186/s12933-015-0272-6.


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encodeId=916f143054eeb, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Tue Sep 22 10:24:00 CST 2015, time=2015-09-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1496270, encodeId=c12714962e071, content=<a href='/topic/show?id=43b6e358710' target=_blank style='color:#2F92EE;'>#硬化性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73587, encryptionId=43b6e358710, topicName=硬化性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d8119265602, createdName=Smile2683, createdTime=Tue Sep 22 10:24:00 CST 2015, time=2015-09-22, status=1, ipAttribution=)]
  5. 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encodeId=916f143054eeb, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Tue Sep 22 10:24:00 CST 2015, time=2015-09-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1496270, encodeId=c12714962e071, content=<a href='/topic/show?id=43b6e358710' target=_blank style='color:#2F92EE;'>#硬化性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73587, encryptionId=43b6e358710, topicName=硬化性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d8119265602, createdName=Smile2683, createdTime=Tue Sep 22 10:24:00 CST 2015, time=2015-09-22, status=1, ipAttribution=)]
    2016-03-05 quxin068
  6. 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    2016-05-25 mnda
  7. 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  8. 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