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Stroke:血管迂曲可能与颈动脉夹层相关

2016-08-29 fsy 译 MedSci原创

夹层是缺血性卒中越来越公认的原因,一般为自发性发生或创伤后发生,并且患者相对年轻。研究人员推测可能存在减弱血管壁的诱发因素,动脉迂曲可能在夹层患者中发生率较高。 研究人员连续纳入了颈动脉夹层(CerAD)患者,这些患者都接受了磁共振血管造影。在一项常规健康检查中,接受磁共振血管造影的年龄和性别相匹配的健康受试者作为对照。迂曲是通过颈动脉和椎动脉(VA)动脉半自动测量获得的。迂曲指数被定义

夹层是缺血性卒中越来越公认的原因,一般为自发性发生或创伤后发生,并且患者相对年轻。研究人员推测可能存在减弱血管壁的诱发因素,动脉迂曲可能在夹层患者中发生率较高。

研究人员连续纳入了颈动脉夹层(CerAD)患者,这些患者都接受了磁共振血管造影。在一项常规健康检查中,接受磁共振血管造影的年龄和性别相匹配的健康受试者作为对照。迂曲是通过颈动脉和椎动脉(VA)动脉半自动测量获得的。迂曲指数被定义为每个动脉[(arc/chord)-1×100]。研究人员使用多变量分析探讨了与CerAD相关的独立危险因素。同时,研究人员根据夹层动脉也进行了亚组分析。

在75例CerAD患者和75名对照参与者之间,血管危险因素没有差异。与对照参与者相比,CerAD患者对侧VA(分别为16.3±6.8 vs 12.1±4.5; P<0.001)和颈动脉(分别为8.8±4.0 vs 7.3±2.9; P=0.01)的迂曲指数较高。VA迂曲(比值比,1.175; P=0.001)与CerAD的存在独立相关。在亚组分析中,57例VA夹层患者的VA迂曲比对照组显著较高(P<0.001),18例颈动脉夹层患者的颈动脉迂曲略高(P=0.05)。

CerAD与颈动脉迂曲有关,这可能会弱化这些患者的颈部血管结构。

原始出处:

Bum Joon Kim,Ewha Yang,Na-Young Kim,et al.Vascular Tortuosity May Be Associated With Cervical Artery Dissection,Stroke,2016.8.29

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    2016-10-06 ylzr123

    赞一个!好文章拜读了,认真学习了。

    0

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    2016-09-05 李东泽

    很好,不错,以后会多学习

    0

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