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SCI REP:风险模型预测乳腺浸润性导管癌患者腋窝淋巴结转移的效果!

2017-06-09 xing.T MedSci原创

由此可见,研究中针对腋窝淋巴结转移建立的风险模型可能易化可乳腺浸润性导管癌患者后续的治疗计划和管理。

近日,Scientific reports 杂志上发表了一篇研究文章,研究人员旨在开发一个风险模型来预测乳腺浸润性导管癌(IDC)患者腋窝淋巴结转移情况,这一风险模型是根据超声、虚拟接触组织超声弹性成像(VTI)和虚拟接触组织成像和量化(VTIQ)和组织学参数来构建的模型。

这项研究共纳入了162例乳腺浸润性导管癌患者,研究人员采用单因素和多因素分析来确定危险因素,并建立风险模型。

研究结果发现162例患者发生腋窝淋巴结转移的患者有64例(39.5%)。腋窝淋巴结转移的风险评分(RS)定义如下:RS=1.3×(如果病灶大小≥20毫米)+2.6×(如果高比宽大的)+2.2×(如果VTI评分≥5)+3.9×(如果组织学分级III)+1.9×(如果C-erbB-2阳性)。该评级体系分为6个阶段(即I期、II期、III期、IV期、V期和VI期)并且发生腋窝淋巴结转移的相关风险率分别为0%(0/19)、6.1%(2/33)、7.7%(3/39)、65.5%(19/29)、92.3%(24/26)和100%(16/16)。

由此可见,研究中针对腋窝淋巴结转移建立的风险模型可能易化可乳腺浸润性导管癌患者后续的治疗计划和管理

原始出处:

Xiao-Long Li,et al. A Risk Model based on Ultrasound, Ultrasound Elastography, and Histologic Parameters for Predicting Axillary Lymph Node Metastasis in Breast Invasive Ductal Carcinoma.Scientific reports. 2017. https://www.nature.com/articles/s41598-017-03582-3#Sec8

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    2017-06-12 虈亣靌

    谢谢分享,很有用

    0

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    2017-06-11 sodoo
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