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Lancet Diabetes Endocrinology:2001-18年糖尿病患者和非糖尿病个体的死亡原因变化

2021-02-08 MedSci原创 MedSci原创

在英国和其他高收入国家中,糖尿病的发病率持续上升,但心血管疾病的死亡率却大大下降!然而,目前关于这些趋势如何改变了既往主要死于血管病的糖尿病患者的死亡原因的数据很少。本研究评估了糖尿病患者的全因死亡率

在英国和其他高收入国家中,糖尿病的发病率持续上升,但血管疾病的死亡率却大大下降!然而,目前关于这些趋势如何改变了既往主要死于血管病的糖尿病患者的死亡原因的数据很少。本研究评估了糖尿病患者的全因死亡率和特定原因死亡率如随时间的变化,死亡率负担的组成如何变化并与非糖尿病人群相比。

研究人员通过分析基础保健记录筛选出了2001年-2018年确诊的313907位糖尿病患者,与国家统计的死亡率数据相关联。

有无糖尿病个体的死亡原因

2001年1月1日-2018年10月31日,糖尿病男性患者和女性患者的总死亡率分别降低了32%和31%。男性患者的死亡率从40.7/1000人·年降至了27.8/1000人·年;女性患者的死亡率从42.7/1000人·年降至了29.5/1000人·年。同时,研究人员还发现非糖尿病患者的死亡率也有相似的下降,因此,在整个研究期间,糖尿病患者和非糖尿病患者之间的死亡率差距仍然无明显变化。

特定原因死亡率的相对变化

12个死亡原因中有10个原因的特异性死亡率都有所降低,除了痴呆和肝病,这两种因素特异性的死亡率不降反升。血管疾病死亡率的大幅度降低导致糖尿病患者的首要死因从心血管原因变成了癌症。

各死亡原因的贡献比例

综上,糖尿病患者血管死亡率的降低伴随着死亡原因的多样化,首要死因也从心血管原因变成了癌症。临床和预防策略应相应改变以适应这种变化趋势,以尽可能降低糖尿病患者的高死亡风险。

原始出处:

Jonathan Pearson-Stuttard, et al. Trends in predominant causes of death in individuals with and without diabetes in England from 2001 to 2018: an epidemiological analysis of linked primary care records. The Lancet Diabetes & Endocrinology. February 04, 2021.

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    2021-11-03 14676011m83暂无昵称

    非常优秀有用

    0

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  5. 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encodeId=933b103416032, content=顶刊就是不一样,质量很高,内容精彩!学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=goodbing, createdTime=Mon Feb 08 18:15:03 CST 2021, time=2021-02-08, status=1, ipAttribution=)]
  6. 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  7. 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encodeId=933b103416032, content=顶刊就是不一样,质量很高,内容精彩!学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=goodbing, createdTime=Mon Feb 08 18:15:03 CST 2021, time=2021-02-08, status=1, ipAttribution=)]
    2021-03-02 howi
  8. 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  9. [GetPortalCommentsPageByObjectIdResponse(id=1902545, encodeId=279519025455f, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Tue Jun 22 00:15:03 CST 2021, time=2021-06-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1066703, encodeId=c7ae1066e03f8, content=非常优秀有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9585140579, createdName=14676011m83暂无昵称, createdTime=Wed Nov 03 21:45:57 CST 2021, time=2021-11-03, status=1, ipAttribution=), 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  10. 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    2021-02-08 goodbing

    顶刊就是不一样,质量很高,内容精彩!学到很多

    0

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