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Sci Rep:老年患者围手术期及麻醉相关心脏骤停的荟萃分析

2017-06-11 MedSci MedSci原创

随着世界老龄化的到来,接受手术治疗的老年患者也越来越多。本次系统性回顾旨在评价麻醉程序以评估老年外科患者围手术期和麻醉相关的心搏停止(CA)发生率的全球数据。使用荟萃回归评价随着时间的推移围手术期和麻醉相关的CA发生率的可利用数据,以及国家的人类发展指数(HDI),采用比例汇总分析比较HDI和时间段的围手术期和麻醉相关CA发生率。Meta回归分析显示,围手术期CA的发生率并没有明显随着时间的推移或

随着世界老龄化的到来,接受手术治疗的老年患者也越来越多。本次系统性回顾旨在评价麻醉程序以评估老年外科患者围手术期和麻醉相关的心搏停止(CA)发生率的全球数据。

使用荟萃回归评价随着时间的推移围手术期和麻醉相关的CA发生率的可利用数据,以及国家的人类发展指数(HDI),采用比例汇总分析比较HDI和时间段的围手术期和麻醉相关CA发生率。

Meta回归分析显示,围手术期CA的发生率并没有明显随着时间的推移或HDI而改变,而麻醉相关的CA的发生率则随时间的延长(P = 0.04  )和高HDI(P = 0.015  )而下降。围手术期和麻醉相关的CA的发生率在高HDI中每10000例麻醉中就有所下降,分别从1990s以前的38.6降低到1999–2017年的7.7(P < 0.001  )和1990s以前的9.2降低到1999–2017年的1.3(P < 0.001  )。低HDI的国家围手术期CA的发生率从1990–2017明显低于高HDI国家(P < 0.001  )。

因此,随着时间的推移,可发现麻醉相关CA发生率降低。围手术期及麻醉相关的CA发生率仅在高HDI事会随时间而下降,1990–2017年期间与高HDI相比,低HDI围手术期CA的发生率高4倍。

原始出处:

Karen S. Braghiroli,José R. C. Braz, et al., Perioperative and anesthesia-related cardiac arrests in geriatric patients: a systematic review using meta-regression analysis. Sci Rep. 2017; 7: 2622. Published online 2017 Jun 1. doi:  10.1038/s41598-017-02745-6.

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  2. [GetPortalCommentsPageByObjectIdResponse(id=2053773, encodeId=fe412053e7341, content=<a href='/topic/show?id=8f5a54442a1' target=_blank style='color:#2F92EE;'>#手术期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54442, encryptionId=8f5a54442a1, topicName=手术期)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/WQ1WyMBGic8d2fKdCe6Cm3vaRh4X8YnlumYndC46iagNCBl9Df8RtoCaQchnFtZldHUctGJjsgsyutUlu8vPq6yQ/132, createdBy=97862500016, createdName=ms3117646317107274, createdTime=Sun Jan 07 18:44:00 CST 2018, time=2018-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1681340, encodeId=024b168134087, content=<a href='/topic/show?id=366b8e2299e' target=_blank style='color:#2F92EE;'>#荟萃#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87229, encryptionId=366b8e2299e, topicName=荟萃)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c12d27855367, createdName=venlin, createdTime=Sun Apr 22 23:44:00 CST 2018, time=2018-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1836911, encodeId=29d2183691166, content=<a href='/topic/show?id=1f188e230c5' target=_blank style='color:#2F92EE;'>#荟萃分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87230, encryptionId=1f188e230c5, topicName=荟萃分析)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b79433, createdName=fangcong, createdTime=Wed Sep 13 00:44:00 CST 2017, time=2017-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209684, encodeId=92b0209684cd, content=学习了谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=d41c2055892, createdName=184****9840, createdTime=Mon Jun 12 07:12:38 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209622, encodeId=95d7209622d4, content=学习了,谢谢作者分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3xJXLtMtt5B40XXuPjn9xn1rBhrM6fHLkX1hI86ZoWoPJkgDkZuJNKkBfBHOcRd1fAdezg7JlHNOokohdAp3WkI/0, createdBy=32c81964262, createdName=1e145228m78(暂无匿称), createdTime=Mon Jun 12 06:07:17 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209509, encodeId=7cc820950914, content=好的,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ad4c106013, createdName=Drhzm308, createdTime=Sun Jun 11 20:32:49 CST 2017, time=2017-06-11, status=1, ipAttribution=)]
    2018-04-22 venlin
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    2017-06-12 184****9840

    学习了谢谢分享。

    0

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    2017-06-12 1e145228m78(暂无匿称)

    学习了,谢谢作者分享!

    0

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    2017-06-11 Drhzm308

    好的,学习了

    0

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