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KIDNEY INT:慢性肾脏病患者疼痛患病率分析

2021-05-03 MedSci原创 MedSci原创

疼痛是慢性肾脏病(CKD)患者一种常见的症状,但其常常未得到充分治疗,所有亚型的CKD患者都承受着很高的疼痛负担。

疼痛是慢性肾脏病(CKD)患者一种常见的症状,但其常常未得到充分治疗,其患病率比普通人群高得多。

近日,肾脏病领域权威杂志kidney international上发表了一篇研究文章,该系统评价旨在综合所有可用的定量证据,以便更好地了解CKD患者的疼痛发生率和疼痛类型。

研究人员检索了四个数据库和灰色文献,检索时间截止至2021年1月15日。研究人员进行了随机效应的荟萃分析,并进行了多个亚组分析和荟萃回归,以进一步探讨研究之间的异质性。研究人员使用Newcastle Ottawa量表评估了纳入研究的质量,并使用GRADE方法确定证据质量水平。

116项研究报告了40678名受试者的数据。荟萃分析的结果显示,疼痛的总体患病率为60%(95%置信区间为56-64),慢性疼痛的总体患病率为48%(42-55),神经性疼痛的患病率为10%(6-15)。与接受透析的患者(63%)(57-68)和未接受透析的CKD患者(63-55)相比,接受肾移植的患者疼痛的发生率较低,为46%(37-56)。在经保守治疗的CKD患者(42%(28-56))或接受透析(45%(36-55))的患者中,肌肉骨骼疼痛似乎是最常见的疼痛表现,而肾移植受者中腹痛最为常见,为41%(7-86)。

由此可见,所有亚型的CKD患者都承受着很高的疼痛负担

原始出处:

Emilie Lambourg,et al.The prevalence of pain among patients with chronic kidney disease using systematic review and meta-analysis.kidney-international.2021.https://doi.org/10.1016/j.kint.2021.03.041

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    2021-08-20 仓央嘉措

    2020年7月16日,国际疼痛学会(The International Association for the Study of Pain, IASP) 对"疼痛"(Pain) 定义进行了修改,并在线发表在其会刊《PAIN》杂志上。

    0

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    2021-05-05 gwc389
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    2021-05-03 ms7000001616476871

    非常值得学习的知识,学习使用进步

    0

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