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Stroke:恶性卒中患者减压颅骨切除术后有创颅内压监测的意义

2020-12-07 MedSci原创 MedSci原创

需要重新评估MCI患者DC术后的ICP,并要求重新确定这些患者的ICP阈值,以确定进一步治疗。

减压性半颅脑切除术(DC)在恶性脑卒中(MCI)中的作用已经明确,但对接受这种手术患者的颅内压(ICP)病程变化知之甚少。近日,血管疾病领域权威杂志Stroke上发表了一篇研究文章,在这项研究中,研究人员旨在调查有创ICP监测在DC后MCI患者中的作用,并假设术后ICP可以预测患者死亡率。

在这项对接受DC的MCI患者进行的回顾性观察研究中,在DC后的头72小时内以小时为间隔连续记录ICP。每小时计算平均ICP,并合并每名患者的ICP。研究人员对每小时平均ICP进行受试者工作特性分析,并按年龄(≥60岁和<60岁)进行了亚组分析。

该研究共分析了111名患者,<60岁的患者死亡率为29%,≥60岁的患者死亡率为41%。

术后头72小时内的10mmHg阈值是MCI患者死亡的可靠预测指标,可接受的灵敏度为70%,特异性高达97%。现有已知的死亡预测因子无法预测死亡。

由此可见,需要重新评估MCI患者DC术后的ICP,并要求重新确定这些患者的ICP阈值,以确定进一步治疗。

原始出处:

Silvia Hernández-Durán.et al.Invasive Monitoring of Intracranial Pressure After Decompressive Craniectomy in Malignant Stroke.stroke.2020.https://www.ahajournals.org/doi/10.1161/STROKEAHA.120.032390

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    2020-12-19 攸风落叶

    厉害

    0

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  6. [GetPortalCommentsPageByObjectIdResponse(id=1877352, encodeId=06d818e735206, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Sat Dec 26 13:48:32 CST 2020, time=2020-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1820283, encodeId=ecf518202835d, content=<a href='/topic/show?id=44a1100485d6' target=_blank style='color:#2F92EE;'>#颅骨切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100485, encryptionId=44a1100485d6, topicName=颅骨切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1f1d390, createdName=feifers, createdTime=Fri Jan 22 12:48:32 CST 2021, time=2021-01-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1720359, encodeId=73451e203591d, content=<a href='/topic/show?id=915c3604e6b' target=_blank style='color:#2F92EE;'>#卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36047, encryptionId=915c3604e6b, topicName=卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=940232842333, createdName=wangyang7969, createdTime=Wed Jul 14 06:48:32 CST 2021, time=2021-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909306, encodeId=50049093067c, content=厉害, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/ibjovs0jKibT3EplYTDpx6KrkzkdYJ9vjHIlWZRPNQNKzyyOzL3IicvvoyakLYSmQpjCicMK5DXqPCRKibZySvNibL8Q/132, createdBy=0cad5249547, createdName=攸风落叶, createdTime=Sat Dec 19 09:10:48 CST 2020, time=2020-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1503564, encodeId=072d1503564a5, content=<a href='/topic/show?id=ac441003921e' target=_blank style='color:#2F92EE;'>#颅内压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100392, encryptionId=ac441003921e, topicName=颅内压)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d96d9662987, createdName=jiadan198785, createdTime=Wed Dec 09 11:48:32 CST 2020, time=2020-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026721, encodeId=afc61026e219f, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Mon Dec 07 23:48:32 CST 2020, time=2020-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=905810, encodeId=ec43905810b4, content=nice , beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=65745442333, createdName=ms2000000302436063, createdTime=Mon Dec 07 21:18:22 CST 2020, time=2020-12-07, status=1, ipAttribution=)]
    2020-12-07 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1877352, encodeId=06d818e735206, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Sat Dec 26 13:48:32 CST 2020, time=2020-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1820283, encodeId=ecf518202835d, content=<a href='/topic/show?id=44a1100485d6' target=_blank style='color:#2F92EE;'>#颅骨切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100485, encryptionId=44a1100485d6, topicName=颅骨切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1f1d390, createdName=feifers, createdTime=Fri Jan 22 12:48:32 CST 2021, time=2021-01-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1720359, encodeId=73451e203591d, content=<a href='/topic/show?id=915c3604e6b' target=_blank style='color:#2F92EE;'>#卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36047, encryptionId=915c3604e6b, topicName=卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=940232842333, createdName=wangyang7969, createdTime=Wed Jul 14 06:48:32 CST 2021, time=2021-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=909306, encodeId=50049093067c, content=厉害, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/ibjovs0jKibT3EplYTDpx6KrkzkdYJ9vjHIlWZRPNQNKzyyOzL3IicvvoyakLYSmQpjCicMK5DXqPCRKibZySvNibL8Q/132, createdBy=0cad5249547, createdName=攸风落叶, createdTime=Sat Dec 19 09:10:48 CST 2020, time=2020-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1503564, encodeId=072d1503564a5, content=<a href='/topic/show?id=ac441003921e' target=_blank style='color:#2F92EE;'>#颅内压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100392, encryptionId=ac441003921e, topicName=颅内压)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d96d9662987, createdName=jiadan198785, createdTime=Wed Dec 09 11:48:32 CST 2020, time=2020-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026721, encodeId=afc61026e219f, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Mon Dec 07 23:48:32 CST 2020, time=2020-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=905810, encodeId=ec43905810b4, content=nice , beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=65745442333, createdName=ms2000000302436063, createdTime=Mon Dec 07 21:18:22 CST 2020, time=2020-12-07, status=1, ipAttribution=)]
    2020-12-07 ms2000000302436063

    nice

    0

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