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TACE联合全身化疗或延长乳腺癌术后肝转移患者生存期

2011-07-31 魏红 医学论坛网

 《癌症研究与临床肿瘤学杂志》(J Cancer Res Clin Oncol)7月26日在线发表的一项研究结果表明,经导管动脉内化疗栓塞(TACE)联合全身化疗(SC)或可延长乳腺癌患者乳房切除术后肝转移者的生存期。   该研究对比了44例接受TACE联合全身化疗的患者(TSC组)和43例接受全身化疗的患者(SC)的转归。   结果显示,从诊断为肝转移

 《癌症研究与临床肿瘤学杂志》(J Cancer Res Clin Oncol)7月26日在线发表的一项研究结果表明,经导管动脉内化疗栓塞(TACE)联合全身化疗(SC)或可延长乳腺癌患者乳房切除术后肝转移者的生存期。

  该研究对比了44例接受TACE联合全身化疗的患者(TSC组)和43例接受全身化疗的患者(SC)的转归。

  结果显示,从诊断为肝转移起的中位随访时间为29个月(范围:0~89个月)。TSC和SC组的的反应率分别为59.1%和34.9%(P<0.05)。 TSC和SC组的1 、2 、3年生存率分别为76.2%、66.7%、47.6%和48.1%、29.6%和7.4%(P=0.027)。原发肿瘤伴雌激素受体阴性、乳房切除术后至肝转移时间不足24个月和只接受全身化疗与患者转归差呈显著独立相关性(P=0.009、 0.023和0.030)。

  相关链接:Treatment outcome of patients with liver-only metastases from breast cancer after mastectomy: a retrospective analysis

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    2011-10-30 shanyongle
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    2012-04-04 grace5700
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