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PET SUVmax不能预测食管癌总生存

2012-03-06 MedSci MedSci原创

 澳大利亚学者2月29日在线发表于《世界外科杂志》(World Journal of Surgery)的一项研究称,不支持采用治疗前PET-CT 最大标准摄取值(SUVmax)预测食管癌患者尤其是已接受新辅助治疗的食管癌患者的预后。   该研究从一个被前瞻性维护的数据库中确定了2001~2010年所有接受食管切除术且有术前PET-CT数据的患者的资料。   结果共确定了103例符合条件的患者

 澳大利亚学者2月29日在线发表于《世界外科杂志》(World Journal of Surgery)的一项研究称,不支持采用治疗前PET-CT 最大标准摄取值(SUVmax)预测食管癌患者尤其是已接受新辅助治疗的食管癌患者的预后。

  该研究从一个被前瞻性维护的数据库中确定了2001~2010年所有接受食管切除术且有术前PET-CT数据的患者的资料。

  结果共确定了103例符合条件的患者的资料。

  82例为腺癌(80%),21例(20%)为鳞状细胞癌。

  57例(55%)接受了新辅助治疗。

  在仅接受手术治疗的患者中,原发肿瘤SUVmax>5.0与预后较差显著相关[危险比(HR)为0.32,P=0.007],但多变量分析并未确认这种显著性(HR为0.65,P=0.43)。

  在已经接受新辅助治疗的患者中,术前SUVmax不能显著预测总生存状况(P=0.10)。

  相关链接:Brown C, Howes B, Jamieson GG, Bartholomeusz D, Zingg U, Sullivan TR, Thompson SK.Accuracy of PET-CT in Predicting Survival in Patients with Esophageal Cancer. World J Surg. 2012 Feb 29.

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    2012-06-01 feather89
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    2012-03-08 zhouqu_8
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