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J Periodontal Res:Tunnel β-磷酸三钙用于损伤拔牙窝内的嵴重建

2020-02-09 lishiting MedSci原创

这篇研究的目的是为了评估tunnel β-TCP块植入颊侧骨壁缺失的拔牙窝内愈合6个月后的组织学疗效。

这篇研究的目的是为了评估tunnel β-TCP块植入颊侧骨壁缺失的拔牙窝内愈合6个月后的组织学疗效。

研究采用有机隧道样的β-磷酸三钙陶瓷制备成tunnel β-磷酸三钙(β-TCP)块。研究采用6只比格犬,将其上颌前磨牙拔除并通过外科手术的方法制备颊侧骨壁缺失的模型,缺损大小为4 mm (mesio-distal) × 5 mm (apico-coronal) × 4 mm (bucco-palatal)。随后,颊侧缺失的拔牙窝采用捏碎的tunnel β-TCP (test)植入至原牙槽嵴的位置或空置(control)。在愈合后的6个月采用组织学/组织形态测定法观察和分析。

结果显示,test部位颊腭侧牙槽嵴的水平厚度明显大于control。Test部位矿化组织的量(57.8% ± 11.1%)明显大于control部位(28.9% ± 8.5%),而control部位的结缔组织量(41.7% ± 6.4%)却明显大于test (19.6% ± 9.2%)。部位之间的基础腔隙单元与骨髓没有显著性差异。Test部位残留的β-TCP为5.8% ± 3.2%。

结论:即使是在愈合后的6个月,与自然愈合的拔牙窝相比,植入tunnel β-TCP块显著限制了缺失颊侧骨壁拔牙窝内牙槽嵴的吸收。

原始出处:

Takahiro Ikawa, Tatsuya Akizuki, et al. Ridge Reconstruction in Damaged Extraction Sockets Using Tunnel β-Tricalcium Phosphate Blocks: A 6-month Histological Study in Beagle Dogs. J Periodontal Res 2020 Jan 27[Online ahead of print] PMID: 31985082  DOI: 10.1111/jre.12735

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  6. [GetPortalCommentsPageByObjectIdResponse(id=1994443, encodeId=76fb19944438d, content=<a href='/topic/show?id=a82156216d3' target=_blank style='color:#2F92EE;'>#拔牙窝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56216, encryptionId=a82156216d3, topicName=拔牙窝)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=baf586, createdName=wangbingxhy, createdTime=Wed Jul 29 23:57:00 CST 2020, time=2020-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1728291, encodeId=86e91e282910d, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Mon Jan 25 04:57:00 CST 2021, time=2021-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1801453, encodeId=7eb118014538c, content=<a href='/topic/show?id=b89ae38472d' target=_blank style='color:#2F92EE;'>#磷酸三钙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73847, encryptionId=b89ae38472d, topicName=磷酸三钙)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5b34252, createdName=chenshujs, createdTime=Thu Nov 12 14:57:00 CST 2020, time=2020-11-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1756738, encodeId=7fea1e56738ad, content=<a href='/topic/show?id=5a9e4e83573' target=_blank style='color:#2F92EE;'>#嵴重建#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47835, encryptionId=5a9e4e83573, topicName=嵴重建)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=04d837217936, createdName=124984edm34暂无昵称, createdTime=Thu Oct 08 19:57:00 CST 2020, time=2020-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1397902, encodeId=e5c6139e902b3, content=<a href='/topic/show?id=8bee565436d' target=_blank style='color:#2F92EE;'>#损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56543, encryptionId=8bee565436d, topicName=损伤)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Tue Feb 11 02:57:00 CST 2020, time=2020-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1574239, encodeId=c90515e4239e4, content=<a href='/topic/show?id=36fc56212c6' target=_blank style='color:#2F92EE;'>#拔牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56212, encryptionId=36fc56212c6, topicName=拔牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9c5216012416, createdName=xre2013, createdTime=Tue Feb 11 02:57:00 CST 2020, time=2020-02-11, status=1, ipAttribution=)]
    2020-02-11 xre2013
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