Baidu
map

NEJM:一例沙门氏菌感染致假性动脉瘤案例报道

2016-05-26 MedSci MedSci原创

男性患者,66岁,既往有高血压病史,因发烧4天和声音嘶哑1天而入院就诊。据该患者称,他没有出现胸痛、咳嗽和呼吸困难等症状。

男性患者,66岁,既往有高血压病史,因发烧4天和声音嘶哑1天而入院就诊。据该患者称,他没有出现胸痛、咳嗽和呼吸困难等症状。 



常规体格检查,其体温为38.7°C,其他的检查项目未见异常。

血清学检查结果显示血白细胞计数升高。

胸片结果显示主动脉弓扩大,随着气管右侧偏移(如图A,箭头)。

胸部计算机断层扫描显示主动脉弓假性动脉瘤(如图B和C,箭头),且被广泛的气体包裹(如图B,C,D,箭头所示)。

血培养结果发现有沙门氏菌感染,最后,会诊医师根据该患者的临床症状及检查结果诊断其为沙门氏菌感染导致的主动脉弓假性动脉瘤。

随即,会诊医师对其应用哌拉西林钠/他唑巴坦钠药物进行抗感染治疗。

不久,该患者因感染形成的假性动脉瘤破裂而坍塌,接受了紧急人工血管置换手术。

术后早期患者康复良好,但在术后几个月内死亡,死因不明。

通常情况下,感染沙门氏菌导致主动脉弓假性动脉瘤的案例是非常罕见的,而一旦患者确诊,发病率和死亡率都非常高。

原始出处

Masao Takagi, M.D., and Mikiro Kato, M.D. Salmonella enterica Aortitis

N Engl J Med 2016; 374:e26May 26, 2016

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=110505, encodeId=3456110505c8, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Sat Sep 03 21:09:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=110506, encodeId=6fad110506ef, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Sat Sep 03 21:09:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1399134, encodeId=5bd01399134a7, content=<a href='/topic/show?id=1e7464490b7' target=_blank style='color:#2F92EE;'>#沙门氏菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64490, encryptionId=1e7464490b7, topicName=沙门氏菌)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/dZj08ckjV0K1emuaDxP7G2DicoLPC5gxtjiatZukfCclP1r3RbxcTgibCpicZkfazrzGUU2iatBBWBNuPTP10a3g5Mw/0, createdBy=12552195639, createdName=lifestar, createdTime=Sat May 28 01:53:00 CST 2016, time=2016-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1447450, encodeId=ad7b144e45059, content=<a href='/topic/show?id=515d2e5538e' target=_blank style='color:#2F92EE;'>#假性动脉瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27553, encryptionId=515d2e5538e, topicName=假性动脉瘤)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/fyRKNyibzABAicp53YP9icFXdxz0NU7qFxPHUvpIndI7G9KBE1szkMibaGgLVxKhV9QlEqPHtlolHibycuROenU7Wdw/132, createdBy=2a4a5352886, createdName=gaoxiaoe, createdTime=Sat May 28 01:53:00 CST 2016, time=2016-05-28, status=1, ipAttribution=)]
    2016-09-03 doctorJiangchao

    继续学习

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=110505, encodeId=3456110505c8, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Sat Sep 03 21:09:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=110506, encodeId=6fad110506ef, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Sat Sep 03 21:09:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1399134, encodeId=5bd01399134a7, content=<a href='/topic/show?id=1e7464490b7' target=_blank style='color:#2F92EE;'>#沙门氏菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64490, encryptionId=1e7464490b7, topicName=沙门氏菌)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/dZj08ckjV0K1emuaDxP7G2DicoLPC5gxtjiatZukfCclP1r3RbxcTgibCpicZkfazrzGUU2iatBBWBNuPTP10a3g5Mw/0, createdBy=12552195639, createdName=lifestar, createdTime=Sat May 28 01:53:00 CST 2016, time=2016-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1447450, encodeId=ad7b144e45059, content=<a href='/topic/show?id=515d2e5538e' target=_blank style='color:#2F92EE;'>#假性动脉瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27553, encryptionId=515d2e5538e, topicName=假性动脉瘤)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/fyRKNyibzABAicp53YP9icFXdxz0NU7qFxPHUvpIndI7G9KBE1szkMibaGgLVxKhV9QlEqPHtlolHibycuROenU7Wdw/132, createdBy=2a4a5352886, createdName=gaoxiaoe, createdTime=Sat May 28 01:53:00 CST 2016, time=2016-05-28, status=1, ipAttribution=)]
    2016-09-03 doctorJiangchao

    继续关注

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=110505, encodeId=3456110505c8, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Sat Sep 03 21:09:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=110506, encodeId=6fad110506ef, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Sat Sep 03 21:09:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1399134, encodeId=5bd01399134a7, content=<a href='/topic/show?id=1e7464490b7' target=_blank style='color:#2F92EE;'>#沙门氏菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64490, encryptionId=1e7464490b7, topicName=沙门氏菌)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/dZj08ckjV0K1emuaDxP7G2DicoLPC5gxtjiatZukfCclP1r3RbxcTgibCpicZkfazrzGUU2iatBBWBNuPTP10a3g5Mw/0, createdBy=12552195639, createdName=lifestar, createdTime=Sat May 28 01:53:00 CST 2016, time=2016-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1447450, encodeId=ad7b144e45059, content=<a href='/topic/show?id=515d2e5538e' target=_blank style='color:#2F92EE;'>#假性动脉瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27553, encryptionId=515d2e5538e, topicName=假性动脉瘤)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/fyRKNyibzABAicp53YP9icFXdxz0NU7qFxPHUvpIndI7G9KBE1szkMibaGgLVxKhV9QlEqPHtlolHibycuROenU7Wdw/132, createdBy=2a4a5352886, createdName=gaoxiaoe, createdTime=Sat May 28 01:53:00 CST 2016, time=2016-05-28, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=110505, encodeId=3456110505c8, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Sat Sep 03 21:09:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=110506, encodeId=6fad110506ef, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Sat Sep 03 21:09:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1399134, encodeId=5bd01399134a7, content=<a href='/topic/show?id=1e7464490b7' target=_blank style='color:#2F92EE;'>#沙门氏菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64490, encryptionId=1e7464490b7, topicName=沙门氏菌)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/dZj08ckjV0K1emuaDxP7G2DicoLPC5gxtjiatZukfCclP1r3RbxcTgibCpicZkfazrzGUU2iatBBWBNuPTP10a3g5Mw/0, createdBy=12552195639, createdName=lifestar, createdTime=Sat May 28 01:53:00 CST 2016, time=2016-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1447450, encodeId=ad7b144e45059, content=<a href='/topic/show?id=515d2e5538e' target=_blank style='color:#2F92EE;'>#假性动脉瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27553, encryptionId=515d2e5538e, topicName=假性动脉瘤)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/fyRKNyibzABAicp53YP9icFXdxz0NU7qFxPHUvpIndI7G9KBE1szkMibaGgLVxKhV9QlEqPHtlolHibycuROenU7Wdw/132, createdBy=2a4a5352886, createdName=gaoxiaoe, createdTime=Sat May 28 01:53:00 CST 2016, time=2016-05-28, status=1, ipAttribution=)]

相关资讯

Cell Host & Microbe:抗生素可扰乱肠道内的氧含量和纤维分解促进致病菌的生长

Cell Host & Microbe:抗生素可扰乱肠道内的氧含量和纤维分解促进致病菌的生长来自加州大学-戴维斯分校的一项新的研究进一步揭示了抗生素治疗的潜在危害性,研究发现抗生素可扰乱肠道内的氧水平和纤维的分解从而促进致病菌的生长繁殖。该研究成果已在线发表于Cell Host & Microbe。20世纪40年代以来抗生素的使用拯救饿无数的生命,但是抗生素耐药性的发生,以及对抗生

气候变暖或促进沙门氏菌爆发

沙门氏菌是一类相对常见的致病菌,其中的一些种类可能造成人类呕吐、发烧和腹泻等症状。而且这种菌常常因为不严格的卫生条件,而被混进食物中导致人们的食物中毒。以前有研究认为,这类菌的突然大量爆发可能与极端的天气相关,但是具体情况还需要进一步验证。美国马里兰州的研究者们分析了过去十年来沙门氏菌的数据,他们将天气与沙门氏菌的爆发建立起了联系。他们的研究认为,过去十年内的气候变暖趋势下导致了一些极端的气候情况

喜(恶)香菜的你可以用这些知识劝解别人

香菜具有多种口味,且可以用于多种菜系和菜谱,最常见于印度菜。但是你知道香菜都有哪些营养价值,又存在哪些潜在风险么?据美国农业部(USDA)调查,两汤匙的香菜种子包含30卡路里的热量,含蛋白质1.2克、脂肪1.8克、碳水化合物5.6克(包括纤维素4克,不含糖),提供维生素K、铁元素、钙元素、维生素C含量占机体日所需的比值分别为68%、10%、8%、4%。 发表在《美国临床营养学杂志》的一项研究表明,

JFP:沙门氏菌可在夹心饼干中存活6个月以上!

乔治亚大学的研究者发现病原体如沙门氏菌可以在曲奇和饼干中存货至少6个月!佐治亚大学农业和环境科学学院杰出的名誉教授Larry Beuchat领导了一项研究,调查导致食源性疾病的细菌能在食物中存活多久。Beuchat说:“越来越多的食源性疾病与摄入受污染的干的食物有关。我们不期望沙门氏菌食物能够在非常干燥的环境中生长。”Beuchat和共同作者David Mann发现,有害细菌不存可以在干燥食物如曲

Am J Med:巨大感染性髂内动脉假性动脉瘤——案例报道

53岁男性反复发热、左腰痛进行性加重2个月,在这之前的几个月患者有盗汗、畏寒、疲劳、咽痛、体重下降10KG。既往史和家族史无特殊。查体:生命体征平稳,腹部无压痛。辅助检查:肌酸激酶升高(233 U/L),红细胞沉降率升高(64 mm/hr),C反应蛋白升高(62.3 mg/L)。血培养D族沙门氏菌阳性。CT血管造影提示靠近在左侧髂总动脉的分叉处有一个巨大的孤立的假动脉瘤,大小83 mm × 92

PLoS ONE:沙门氏菌引发感染的分子机制

近日,刊登在国际杂志PLoS ONE上的一篇研究论文中,来自诺维奇生物科学研究院的研究人员通过研究揭开了沙门氏菌组织其进行感染所需的基因表达的分子机制。 沙门氏菌是一种食源性致病菌,在很多时候其可以克服机体的天然防御屏障从而成功入侵我们的机体,因此理解其入侵机体的分子机制对于开发新型抑制策略来有效控制沙门氏菌感染非常重要。 大多数沙门氏菌感染会导致胃肠炎,细菌可以侵入到机体肠道的上皮细胞中

Baidu
map
Baidu
map
Baidu
map