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J Oral Biol Craniofac Res:壳聚糖促进拔牙窝伤口愈合的有效性

2018-11-22 MedSci MedSci原创

壳聚糖可促进伤口愈合并诱导骨形成。本研究旨在评估基于壳聚糖的敷料在下颌第三磨牙拔除后伤口愈合中的有效性。 27名患者同时拔除无症状对称下颌第三磨牙,并将壳聚糖敷料置于试验侧的拔牙窝内。使用0至10的疼痛评分在VAS上记录疼痛评分。比较右侧和左侧的伤口愈合情况。通过观察骨板硬化和提取窝密度来评估X线结果。 结果,测试组在所有时间间隔内患者的疼痛感更强,并且阻生部位的平均疼痛评分明显高于已

壳聚糖可促进伤口愈合并诱导骨形成。本研究旨在评估基于壳聚糖的敷料在下颌第三磨牙拔除后伤口愈合中的有效性。

27名患者同时拔除无症状对称下颌第三磨牙,并将壳聚糖敷料置于试验侧的拔牙窝内。使用0至10的疼痛评分在VAS上记录疼痛评分。比较右侧和左侧的伤口愈合情况。通过观察骨板硬化和提取窝密度来评估X线结果。

结果,测试组在所有时间间隔内患者的疼痛感更强,并且阻生部位的平均疼痛评分明显高于已萌出的部位。在伤口愈合的情况下,测试组优于对照。萌出牙齿的愈合明显好于阻生牙齿的部位。在第二周,12个位点在壳聚糖处理组中显示出比对照组中的3个位点更好的X线结果。在第3个月,14个位点显示壳聚糖处理组的骨形成改善,而对照组为4个。与已萌出牙齿组相比,在2周和3个月时,阻生齿组在试验侧X线结果更好。

综上所述,该研究结果表明,壳聚糖可有效促进拔牙后拔牙后伤口愈合和早期成骨。我们建议在拔牙后应将壳聚糖敷料用于已萌牙齿的牙槽窝内,但应避免在未矫正或受影响的牙齿情况下使用。

原始出处:

Akshat Gupta, Vidya Rattan, Sachin Rai. Efficacy of Chitosan in promoting wound healing in extraction socket: A prospective study. J Oral Biol Craniofac Res. 2019 Jan-Mar; 9(1): 91–95.

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    2019-08-05 小几洁
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    2019-05-22 sunylz
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  5. 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  6. 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  7. 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GetPortalCommentsPageByObjectIdResponse(id=1309883, encodeId=468713098834d, content=<a href='/topic/show?id=5e6926003ae' target=_blank style='color:#2F92EE;'>#伤口愈合#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26003, encryptionId=5e6926003ae, topicName=伤口愈合)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8949377, createdName=chenzhuanggui, createdTime=Fri Nov 23 16:19:00 CST 2018, time=2018-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1574233, encodeId=146415e4233cd, content=<a href='/topic/show?id=36fc56212c6' target=_blank style='color:#2F92EE;'>#拔牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56212, encryptionId=36fc56212c6, topicName=拔牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9c5216012416, createdName=xre2013, createdTime=Fri Nov 23 16:19:00 CST 2018, time=2018-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1582423, encodeId=d8b215824234d, content=<a href='/topic/show?id=bda942398cd' target=_blank style='color:#2F92EE;'>#壳聚糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42398, encryptionId=bda942398cd, topicName=壳聚糖)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76f716920725, createdName=dlwang_26703132, createdTime=Fri Nov 23 16:19:00 CST 2018, time=2018-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=353311, encodeId=c5f735331170, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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    2018-11-23 xre2013
  8. [GetPortalCommentsPageByObjectIdResponse(id=1956732, encodeId=99831956e325e, content=<a href='/topic/show?id=7647e210ac' target=_blank style='color:#2F92EE;'>#FAC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7210, encryptionId=7647e210ac, topicName=FAC)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/B389FA68ECBF51BE2FE14093CF61F6AE/100, createdBy=eb8e2500096, createdName=夏天与十三菇凉, createdTime=Mon Dec 24 20:19:00 CST 2018, time=2018-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020514, encodeId=5aae20205142a, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Mon Aug 05 05:19:00 CST 2019, time=2019-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1918412, encodeId=730c1918412cf, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Wed May 22 03:19:00 CST 2019, time=2019-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1994441, encodeId=becd1994441d3, content=<a href='/topic/show?id=a82156216d3' target=_blank style='color:#2F92EE;'>#拔牙窝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56216, encryptionId=a82156216d3, topicName=拔牙窝)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=baf586, createdName=wangbingxhy, createdTime=Fri Jun 14 12:19:00 CST 2019, time=2019-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1767567, encodeId=894b1e6756782, content=<a href='/topic/show?id=64f5343e2f' target=_blank style='color:#2F92EE;'>#Biol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3437, encryptionId=64f5343e2f, topicName=Biol)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=446937890434, createdName=12498ebem31暂无昵称, createdTime=Sat Feb 16 03:19:00 CST 2019, time=2019-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1309883, encodeId=468713098834d, content=<a href='/topic/show?id=5e6926003ae' target=_blank style='color:#2F92EE;'>#伤口愈合#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26003, encryptionId=5e6926003ae, topicName=伤口愈合)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8949377, createdName=chenzhuanggui, createdTime=Fri Nov 23 16:19:00 CST 2018, time=2018-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1574233, encodeId=146415e4233cd, content=<a href='/topic/show?id=36fc56212c6' target=_blank style='color:#2F92EE;'>#拔牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56212, encryptionId=36fc56212c6, topicName=拔牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9c5216012416, createdName=xre2013, createdTime=Fri Nov 23 16:19:00 CST 2018, time=2018-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1582423, encodeId=d8b215824234d, content=<a href='/topic/show?id=bda942398cd' target=_blank style='color:#2F92EE;'>#壳聚糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42398, encryptionId=bda942398cd, topicName=壳聚糖)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76f716920725, createdName=dlwang_26703132, createdTime=Fri Nov 23 16:19:00 CST 2018, time=2018-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=353311, encodeId=c5f735331170, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRkia1DP5MpwEgtXo1XhXA11xD6MWKxunAZFXKSNic0fWHUQx83oNHPlRMxxIctM83QKeCLkJpMibibiaC/0, createdBy=7e581734408, createdName=深海的鱼, createdTime=Thu Nov 22 06:51:42 CST 2018, time=2018-11-22, status=1, ipAttribution=)]
  9. [GetPortalCommentsPageByObjectIdResponse(id=1956732, encodeId=99831956e325e, content=<a href='/topic/show?id=7647e210ac' target=_blank style='color:#2F92EE;'>#FAC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7210, encryptionId=7647e210ac, topicName=FAC)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/B389FA68ECBF51BE2FE14093CF61F6AE/100, createdBy=eb8e2500096, createdName=夏天与十三菇凉, createdTime=Mon Dec 24 20:19:00 CST 2018, time=2018-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020514, encodeId=5aae20205142a, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], 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GetPortalCommentsPageByObjectIdResponse(id=1309883, encodeId=468713098834d, content=<a href='/topic/show?id=5e6926003ae' target=_blank style='color:#2F92EE;'>#伤口愈合#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26003, encryptionId=5e6926003ae, topicName=伤口愈合)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8949377, createdName=chenzhuanggui, createdTime=Fri Nov 23 16:19:00 CST 2018, time=2018-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1574233, encodeId=146415e4233cd, content=<a href='/topic/show?id=36fc56212c6' target=_blank style='color:#2F92EE;'>#拔牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56212, encryptionId=36fc56212c6, topicName=拔牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9c5216012416, createdName=xre2013, createdTime=Fri Nov 23 16:19:00 CST 2018, time=2018-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1582423, encodeId=d8b215824234d, content=<a href='/topic/show?id=bda942398cd' target=_blank style='color:#2F92EE;'>#壳聚糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42398, encryptionId=bda942398cd, topicName=壳聚糖)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76f716920725, createdName=dlwang_26703132, createdTime=Fri Nov 23 16:19:00 CST 2018, time=2018-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=353311, encodeId=c5f735331170, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRkia1DP5MpwEgtXo1XhXA11xD6MWKxunAZFXKSNic0fWHUQx83oNHPlRMxxIctM83QKeCLkJpMibibiaC/0, createdBy=7e581734408, createdName=深海的鱼, createdTime=Thu Nov 22 06:51:42 CST 2018, time=2018-11-22, status=1, ipAttribution=)]
    2018-11-22 深海的鱼

    学习学习学习

    0

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