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JAHA:长期暴露于空气污染与心衰患者30天再入院率和就诊次数相关

2021-05-05 MedSci原创 MedSci原创

鉴于心力衰竭患者的住院和再入院率较高,这些结果也是对可改善的环境危险因素的重要见解,这些因素可改善心衰患者的预后并减少医院资源使用。

长期暴露于环境空气污染是普通人群住院的重要危险因素。但是,目前缺乏关于长期暴露于空气污染是否是再住院危险因素的信息,尤其是对于再入院率较高的个体而言。

近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员确定了20920名心力衰竭患者的再入院次数和医院总就诊次数(门诊就诊+急诊就诊+住院次数)。

研究人员使用准Poisson回归模型将心力衰竭诊断之日的年平均细颗粒物与医院就诊次数和30天再入院次数相关联。研究人员同时使用逆概率权重来平衡混杂因素的分布并针对竞争性死亡风险进行调整。

根据年龄、种族、性别、吸烟状况、城市化程度、诊断年份、短期细颗粒物暴露、合并症和社会经济状况对模型进行了调整。细颗粒物每增加1 µg/m3,受试者就诊总次数增加9.31%(95%CI为7.85%-10.8%),而总住院次数增加4.35%(95%CI为1.12%-7.68%),并且30天再入院率增加14.2%(95%CI为8.41%-20.2%)。相关性对于不同的建模方法仍较明显。

由此可见,这些结果凸显了空气污染在医院使用中尤其是在医院就诊和再入院方面可能发挥着作用。鉴于心力衰竭患者的住院和再入院率较高,这些结果也是对可改善的环境危险因素的重要见解,这些因素可改善心衰患者的预后并减少医院资源使用

原始出处:

Cavin K. Ward‐Caviness.et al.Long‐Term Exposure to Particulate Air Pollution Is Associated With 30‐Day Readmissions and Hospital Visits Among Patients With Heart Failure.J AM HEART ASSOC.2021.https://www.ahajournals.org/doi/full/10.1161/JAHA.120.019430

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    2021-07-12 smlt2008
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    2021-05-14 ms3000000450197257

    学习了

    0

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    2021-05-07 zhaohui6731
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