Baidu
map

Med Sci Sport Exer:不同强度水平的体力活动改变老年人炎症的研究

2018-08-04 郝丽 北体大运动处方研究中心

老年人低度慢性炎症是导致许多年龄相关疾病的原因。体内炎症标志物的不断升高与糖尿病风险有关并以代谢综合征的形式呈现,它表现为一系列的代谢失调,其中包括腹型肥胖、高血压、高脂血症等。

老年人低度慢性炎症是导致许多年龄相关疾病的原因。体内炎症标志物的不断升高与糖尿病风险有关并以代谢综合征的形式呈现,它表现为一系列的代谢失调,其中包括腹型肥胖、高血压、高脂血症等。C反应蛋白(CPR)和纤维蛋白原是用来研究系统炎症与年龄相关疾病的重要指标。CPR和纤维蛋白原与男性、女性的CVD风险有关,有些研究称这与内皮细胞紊乱有关。值得注意的CPR和纤维蛋白原与慢性病和全因死亡率的关系有性别差异。与男性相比,女性纤维蛋白原与BMI指数间的关系有2倍高。

尽管体力活动和代谢性疾病的关系已得到很好的证明,但是系统性标志物的关系最近也引发大量关注。低强度和中等强度体力活动及静坐时间与系统标志物相关。同期替代模型被用来研究体力活动与全因死亡率、血管危险因素和聚集性代谢危险的关系。

目的:

客观测量体力活动水平对老年女性验证标志物及不同水平代谢风险的影响

方法:

利用加速度计测量社区常住老年女性(n=111;年龄65-70yr)的日常静坐时间、低强度体力活动时间(LPA)、中等到较大体力活动活动时间(MVPA);收集IBD%E8%AF%8A%E6%B2%BB%E8%BF%87%E7%A8%8B%E4%B8%AD%E7%9A%84%E8%AF%84%E4%BC%B0-Part%202" target="_blank">血液指标测量炎症标志物C反应蛋白(CRP)、纤维蛋白原、脂联素。根据代谢综合征的定义确定代谢风险。利用线性回归模型进行分析。

结果:

重新分配30天的静坐时间替代低强度体力活动时间(LPA)或者中等到较大体力活动活动时间(MVPA),纤维蛋白水平降低;利用低强度体力活动时间(LPA)代替中等到较大体力活动活动时间(MVPA)相关效应却不明显。相反利用中等到较大体力活动活动时间(MVPA)代替静坐时间,相关效应却很明显,CPR水平降低,但利用低强度运动时间代替静坐时间却没有发现有明显变化。

结论:

研究显示了用各种不同类型强度的运动代替静坐时间对老年女性急性期炎症蛋白会有影响。不同体力活动对炎症标志物影响不同。用轻体力活动代替静坐时间仍然会降低CRP但纤维蛋白不会减少。体力活动会改变肝脏CRP的释放。不同强度的运动能改变老年女性系统炎症反应。

原始出处:

Nilsson A, Bergens O, Kadi F. Physical Activity Alters Inflammation in Older Adults by Different Intensity Levels[J]. Medicine & Science in Sports & Exercise, 2018, 50(7): 1502-1507.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=336821, encodeId=362f3368214e, content=学习了谢谢了, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Mon Aug 06 09:56:17 CST 2018, time=2018-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1609021, encodeId=9090160902114, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Mon Aug 06 00:32:00 CST 2018, time=2018-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=336283, encodeId=44a7336283e9, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sat Aug 04 10:29:33 CST 2018, time=2018-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=336269, encodeId=241233626904, content=阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Sat Aug 04 10:18:47 CST 2018, time=2018-08-04, status=1, ipAttribution=)]
    2018-08-06 186****0580(小山羊)

    学习了谢谢了

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=336821, encodeId=362f3368214e, content=学习了谢谢了, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Mon Aug 06 09:56:17 CST 2018, time=2018-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1609021, encodeId=9090160902114, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Mon Aug 06 00:32:00 CST 2018, time=2018-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=336283, encodeId=44a7336283e9, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sat Aug 04 10:29:33 CST 2018, time=2018-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=336269, encodeId=241233626904, content=阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Sat Aug 04 10:18:47 CST 2018, time=2018-08-04, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=336821, encodeId=362f3368214e, content=学习了谢谢了, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Mon Aug 06 09:56:17 CST 2018, time=2018-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1609021, encodeId=9090160902114, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Mon Aug 06 00:32:00 CST 2018, time=2018-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=336283, encodeId=44a7336283e9, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sat Aug 04 10:29:33 CST 2018, time=2018-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=336269, encodeId=241233626904, content=阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Sat Aug 04 10:18:47 CST 2018, time=2018-08-04, status=1, ipAttribution=)]
    2018-08-04 飛歌

    学习了很有用

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=336821, encodeId=362f3368214e, content=学习了谢谢了, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Mon Aug 06 09:56:17 CST 2018, time=2018-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1609021, encodeId=9090160902114, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Mon Aug 06 00:32:00 CST 2018, time=2018-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=336283, encodeId=44a7336283e9, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sat Aug 04 10:29:33 CST 2018, time=2018-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=336269, encodeId=241233626904, content=阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Sat Aug 04 10:18:47 CST 2018, time=2018-08-04, status=1, ipAttribution=)]
    2018-08-04 sunfeifeiyang

    0

相关资讯

Med Sci Sports Exerc:客观测量的体力活动与膝关节骨性关节炎的发生风险

膝关节骨性关节炎(OA)会限制膝关节的功能及活动,影响生活质量,是膝关节置换术后的主要并发症且与大量的医疗支出相关。体力活动会增加膝关节压力,但体力活动强度与OA发生风险的增加之间的关系是不清楚的。

Med Sci Sports Exerc:童年及成年时期所处的社会经济环境对体力活动不足的影响

体力活动不足的生活模式可能与童年时期的生活状况有关,然而这种关联的证据和其影响途径是缺乏的,本研究通过对大规模数据的调查,研究童年和成年时期生活的社会经济环境与体力活动不足(水平和发展情况)之间的关联。

JAHA:植入装置测量的体力活动可预测房性心律失常和患者预后!

由此可见,在植入ICD的心衰患者中,无论患者的基线特征如何,低水平的PA与房性心律失常的风险有较高的相关性。此外,较低的每日PA可以预测患者死亡或心衰住院。

Brit J Cancer:成年后体重指数、体力活动与多发性骨髓瘤风险!

由此可见,这些发现表明成年早期和成年后较高的BMI是MM的危险因素。

PLos One:SLE女性患者中体力活动和久坐时间与动脉硬化的关联

SLE患者中PA强度水平和久坐时间与动脉硬化无关。

2018 EULAR建议:炎性关节炎与骨关节炎患者的体力活动

2018年7月,欧洲抗风湿病联盟(EULAR)发布了炎性关节炎与骨关节炎患者的体力活动建议,规律体力活动越来越多地在风湿病和肌肉疾病人群和一般人群中进行,本文主要针对炎性关节炎与骨关节炎患者的体力活动提出指导建议。

Baidu
map
Baidu
map
Baidu
map