Baidu
map

JCC:胃肠道超声检查在监测妊娠炎症性肠病患者中的作用

2020-05-03 MedSci原创 MedSci原创

炎症性肠病(IBD)的治疗管理在妇女生育期间会受到影响,而胃肠超声检查(GIUS)可以准确识别非孕妇IBD患者的疾病活动,本项研究旨在确定GIUS在评估妊娠过程中IBD的可行性和准确性。

背景和目标: 炎症性肠病(IBD)的治疗管理在妇女生育期间会受到影响,而胃肠超声检查(GIUS)可以准确识别非孕妇IBD患者的疾病活动,本项研究旨在确定GIUS在评估妊娠过程中IBD的可行性和准确性。

方法: 研究人员对IBD妇女在怀孕期间接受GIUS进行一项多中心观察性研究。临床医生评估了四个结肠段和末端回肠和疾病活动的程度。同时记录子宫的位置。将GIUS疾病活动(肠壁厚度> 3mm)与生化疾病活动(粪便钙卫蛋白>100μg/ g)进行比较。

结果: 本项研究共包括90例患者和127例GIUS检查(中位妊娠19周,范围4-33)。在116/127(91%)扫描中获得了足够的结肠视图。<20周的62/67(93%)扫描和20-26周的30/51(59%)扫描获得了足够的回肠视图。肠壁厚度与钙卫蛋白之间存在正相关(r = 0.26,p = 0.03)。与钙卫蛋白相比,GIUS的特异性为83%,敏感性为74%,阴性预测值为90%。

结论: GIUS是监测妊娠IBD的可行且准确的方法。在大多数妊娠20周以内的患者中,可以获得足够的GIUS对结肠和回肠末端的视野。超过20周,GIUS可以很好地观察结肠,但是回肠末端变得难以评估。

原始出处:

Emma Flanagan. Et al. Monitoring Inflammatory Bowel Disease in Pregnancy using Gastrointestinal Ultrasonography. Journal of Crohn's and Colitis.2020.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1934272, encodeId=770b19342e24f, content=<a href='/topic/show?id=b328833569c' target=_blank style='color:#2F92EE;'>#胃肠道超声#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83356, encryptionId=b328833569c, topicName=胃肠道超声)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Mon Mar 15 12:04:22 CST 2021, time=2021-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284317, encodeId=68d1128431ee6, content=<a href='/topic/show?id=d27a9280461' target=_blank style='color:#2F92EE;'>#超声检查#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92804, encryptionId=d27a9280461, topicName=超声检查)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=649f191, createdName=zzc2211, createdTime=Tue May 05 08:04:22 CST 2020, time=2020-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1346319, encodeId=12381346319cc, content=<a href='/topic/show?id=339e8332035' target=_blank style='color:#2F92EE;'>#胃肠道#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83320, encryptionId=339e8332035, topicName=胃肠道)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e03212, createdName=liao1619, createdTime=Tue May 05 08:04:22 CST 2020, time=2020-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1547322, encodeId=9a5f154e322a7, content=<a href='/topic/show?id=4ef26e01766' target=_blank style='color:#2F92EE;'>#炎症性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67017, encryptionId=4ef26e01766, topicName=炎症性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=09e813968720, createdName=12498dd9m15暂无昵称, createdTime=Tue May 05 08:04:22 CST 2020, time=2020-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1600052, encodeId=2fc61600052a7, content=<a href='/topic/show?id=508e6e03203' target=_blank style='color:#2F92EE;'>#炎症性肠病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67032, encryptionId=508e6e03203, topicName=炎症性肠病患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9fa18776644, createdName=huangshifeng, createdTime=Tue May 05 08:04:22 CST 2020, time=2020-05-05, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1934272, encodeId=770b19342e24f, content=<a href='/topic/show?id=b328833569c' target=_blank style='color:#2F92EE;'>#胃肠道超声#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83356, encryptionId=b328833569c, topicName=胃肠道超声)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Mon Mar 15 12:04:22 CST 2021, time=2021-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284317, encodeId=68d1128431ee6, content=<a href='/topic/show?id=d27a9280461' target=_blank style='color:#2F92EE;'>#超声检查#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92804, encryptionId=d27a9280461, topicName=超声检查)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=649f191, createdName=zzc2211, createdTime=Tue May 05 08:04:22 CST 2020, time=2020-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1346319, encodeId=12381346319cc, content=<a href='/topic/show?id=339e8332035' target=_blank style='color:#2F92EE;'>#胃肠道#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83320, encryptionId=339e8332035, topicName=胃肠道)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e03212, createdName=liao1619, createdTime=Tue May 05 08:04:22 CST 2020, time=2020-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1547322, encodeId=9a5f154e322a7, content=<a href='/topic/show?id=4ef26e01766' target=_blank style='color:#2F92EE;'>#炎症性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67017, encryptionId=4ef26e01766, topicName=炎症性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=09e813968720, createdName=12498dd9m15暂无昵称, createdTime=Tue May 05 08:04:22 CST 2020, time=2020-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1600052, encodeId=2fc61600052a7, content=<a href='/topic/show?id=508e6e03203' target=_blank style='color:#2F92EE;'>#炎症性肠病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67032, encryptionId=508e6e03203, topicName=炎症性肠病患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9fa18776644, createdName=huangshifeng, createdTime=Tue May 05 08:04:22 CST 2020, time=2020-05-05, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1934272, encodeId=770b19342e24f, content=<a href='/topic/show?id=b328833569c' target=_blank style='color:#2F92EE;'>#胃肠道超声#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83356, encryptionId=b328833569c, topicName=胃肠道超声)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Mon Mar 15 12:04:22 CST 2021, time=2021-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284317, encodeId=68d1128431ee6, content=<a href='/topic/show?id=d27a9280461' target=_blank style='color:#2F92EE;'>#超声检查#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92804, encryptionId=d27a9280461, topicName=超声检查)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=649f191, createdName=zzc2211, createdTime=Tue May 05 08:04:22 CST 2020, time=2020-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1346319, encodeId=12381346319cc, content=<a href='/topic/show?id=339e8332035' target=_blank style='color:#2F92EE;'>#胃肠道#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83320, encryptionId=339e8332035, topicName=胃肠道)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e03212, createdName=liao1619, createdTime=Tue May 05 08:04:22 CST 2020, time=2020-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1547322, encodeId=9a5f154e322a7, content=<a href='/topic/show?id=4ef26e01766' target=_blank style='color:#2F92EE;'>#炎症性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67017, encryptionId=4ef26e01766, topicName=炎症性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=09e813968720, createdName=12498dd9m15暂无昵称, createdTime=Tue May 05 08:04:22 CST 2020, time=2020-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1600052, encodeId=2fc61600052a7, content=<a href='/topic/show?id=508e6e03203' target=_blank style='color:#2F92EE;'>#炎症性肠病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67032, encryptionId=508e6e03203, topicName=炎症性肠病患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9fa18776644, createdName=huangshifeng, createdTime=Tue May 05 08:04:22 CST 2020, time=2020-05-05, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1934272, encodeId=770b19342e24f, content=<a href='/topic/show?id=b328833569c' target=_blank style='color:#2F92EE;'>#胃肠道超声#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83356, encryptionId=b328833569c, topicName=胃肠道超声)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Mon Mar 15 12:04:22 CST 2021, time=2021-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284317, encodeId=68d1128431ee6, content=<a href='/topic/show?id=d27a9280461' target=_blank style='color:#2F92EE;'>#超声检查#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92804, encryptionId=d27a9280461, topicName=超声检查)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=649f191, createdName=zzc2211, createdTime=Tue May 05 08:04:22 CST 2020, time=2020-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1346319, encodeId=12381346319cc, content=<a href='/topic/show?id=339e8332035' target=_blank style='color:#2F92EE;'>#胃肠道#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83320, encryptionId=339e8332035, topicName=胃肠道)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e03212, createdName=liao1619, createdTime=Tue May 05 08:04:22 CST 2020, time=2020-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1547322, encodeId=9a5f154e322a7, content=<a href='/topic/show?id=4ef26e01766' target=_blank style='color:#2F92EE;'>#炎症性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67017, encryptionId=4ef26e01766, topicName=炎症性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=09e813968720, createdName=12498dd9m15暂无昵称, createdTime=Tue May 05 08:04:22 CST 2020, time=2020-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1600052, encodeId=2fc61600052a7, content=<a href='/topic/show?id=508e6e03203' target=_blank style='color:#2F92EE;'>#炎症性肠病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67032, encryptionId=508e6e03203, topicName=炎症性肠病患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9fa18776644, createdName=huangshifeng, createdTime=Tue May 05 08:04:22 CST 2020, time=2020-05-05, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1934272, encodeId=770b19342e24f, content=<a href='/topic/show?id=b328833569c' target=_blank style='color:#2F92EE;'>#胃肠道超声#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83356, encryptionId=b328833569c, topicName=胃肠道超声)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Mon Mar 15 12:04:22 CST 2021, time=2021-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284317, encodeId=68d1128431ee6, content=<a href='/topic/show?id=d27a9280461' target=_blank style='color:#2F92EE;'>#超声检查#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92804, encryptionId=d27a9280461, topicName=超声检查)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=649f191, createdName=zzc2211, createdTime=Tue May 05 08:04:22 CST 2020, time=2020-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1346319, encodeId=12381346319cc, content=<a href='/topic/show?id=339e8332035' target=_blank style='color:#2F92EE;'>#胃肠道#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83320, encryptionId=339e8332035, topicName=胃肠道)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e03212, createdName=liao1619, createdTime=Tue May 05 08:04:22 CST 2020, time=2020-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1547322, encodeId=9a5f154e322a7, content=<a href='/topic/show?id=4ef26e01766' target=_blank style='color:#2F92EE;'>#炎症性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67017, encryptionId=4ef26e01766, topicName=炎症性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=09e813968720, createdName=12498dd9m15暂无昵称, createdTime=Tue May 05 08:04:22 CST 2020, time=2020-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1600052, encodeId=2fc61600052a7, content=<a href='/topic/show?id=508e6e03203' target=_blank style='color:#2F92EE;'>#炎症性肠病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67032, encryptionId=508e6e03203, topicName=炎症性肠病患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9fa18776644, createdName=huangshifeng, createdTime=Tue May 05 08:04:22 CST 2020, time=2020-05-05, status=1, ipAttribution=)]

相关资讯

IBD:基质金属蛋白酶3可以预测英夫利昔单抗治疗的炎症性肠病患者的治疗反应

炎症性肠病(IBD)使用抗TNF药物治疗,以前的证据表明,基质金属蛋白酶3(MMP3)对英夫利昔单抗(IFX)的作用是导致丧失治疗应答的一种机制。

GUT:抗TNF治疗可以降低炎症性肠病患者的急性动脉事件

有研究报道,IBD患者发生急性动脉事件的风险明显增加,而抗肿瘤坏死因子(TNF)药物和硫嘌呤类药物可通过其抗炎特性降低急性动脉事件的风险。

AP&T:老年炎症性肠病患者感染或癌症风险更高

对于老年炎症性肠病(IBD)患者,与生物疗法相关的感染和癌症风险存在不确定性。本项研究旨在探究老年炎症性肠病患者感染或癌症风险。

JGH OPEN:TNF-α抑制剂有效降低了炎症性肠病患者紧急事件的发生率

严重的溃疡性结肠炎(UC)可能威胁生命。TNF‐α抑制剂(英夫利昔单抗)是治疗急性严重性UC的特效药物。

Clinical Gastroenterology Hepatology:炎症性肠病增加了2型糖尿病的发病风险

肠道也是调节体内葡萄糖的稳态的重要器官,但尚不清楚慢性肠道炎症是否会影响2型糖尿病的风险。因此,在本项研究中研究人员调查了炎症性肠病(IBD)患者的2型糖尿病的长期风险。

Dig Liver Dis: 抗TNF-α疗法对炎性肠病患者血红蛋白水平的影响

肿瘤坏死因子-α(TNF-α)参与诱发炎症性肠病造成的贫血。抗TNF-α剂对炎症性肠病(IBD)贫血的潜在作用仍然未知。因此,本项研究旨在对其进行相关研究。

Baidu
map
Baidu
map
Baidu
map