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双侧肾上腺区肿块,诊断是?

2019-11-19 不详 影像园

双侧肾上腺区肿块,诊断是?

【所属科室】

泌尿外科

【基本资料】

男,58岁

【主诉】

体检发现双侧肾上腺占位20日

【现病史】

20天前,患者体检时发现左侧肾上腺区占位,余无明显异常。

【既往史】

1. 十二指肠球部溃疡病史多年;2. 确诊糖尿病1月余,现口服二甲双胍片控制血糖,控制情况不详。

【实验室检查】 

肾上腺功能:1: 醛固酮 123.39 pg/ml,2: 血管紧张素II 178.56 pg/ml,3: 皮质醇 15.63 μg/dl,4: 促肾上腺皮质激素 69.77 pg/ml,5: 血浆肾素活性测定 69.93 pg/ml↑。

【影像图片】







【讨论问题】诊断

【讨论】

评论:双侧肾上腺区软组织肿块,边界清晰,密度不均,内见多发斑片状低密度影。双侧肾上腺未见显示。增强检查,病灶不均匀强化,呈显著渐进性强化,内部见多发无强化区。
 
【结果】

术中所见:

左肾上极内侧处见肾上腺包块1个,呈圆形,表面光滑,直径约5cm,与周围组织明显粘连,完整切除包块及部分肾上腺组织。

病理结果:

左肾上腺结核。
 
【病例小结】

肾上腺结核主要表现为肾上腺功能低下,如皮肤和粘膜色素沉着、疲乏无力、食欲不振、体重减轻、低血压和精神症状等,甚至出现肾上腺皮质危象。常伴有其他部位原发结核病变。

病理改变:肾上腺实质破坏,表现为肾上腺结节、肉芽组织、干酪样坏死、钙化等。

CT表现:干酪化期表现为双侧肾上腺增大,形成不规则肿块,且与肾上腺长轴一致,肿块密度不均,内有多发低密度区,代表干酪样坏死区。可伴有点状钙化。增强检查,肿块周边及内隔发生强化,其内低密度区无强化;钙化期双侧肾上腺弥漫性钙化,其形态和方向与肾上腺走行一致。
慢性原发性肾上腺功能减退,又称Addison综合征,表现为肾上腺功能减低。其常见病因包括:自身免疫性肾上腺炎、肾上腺结核、感染、转移瘤、淀粉样变性、化疗及术后、药物等因素。

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    2019-11-21 cnxcy
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