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NEJM:饮食的血糖指数,血糖负荷与心血管疾病的相关性研究

2021-02-25 MedSci原创 MedSci原创

高血糖指数饮食增加心血管疾病及死亡风险

目前,大多数关于血糖指数与血管疾病之间关系的数据来自高收入的西方国家,而来自中低收入的非西方国家相关数据十分有限。

近日研究人员开展了一项庞大的,地理上多样化人口数据研究,收集5大洲,137851名35-70岁参与者数据,分别来自4个高收入国家(加拿大、瑞典、沙特阿拉伯和阿拉伯联合酋长国)、11个中等收入国家(阿根廷、巴西、智利、中国、哥伦比亚、伊朗、马来西亚、巴勒斯坦领土、波兰、南非和土耳其)和5个低收入国家(孟加拉国、印度、巴基斯坦、坦桑尼亚和津巴布韦),平均随访9.5年,使用特定国家的食物问卷来确定参与者饮食摄入量,并根据七类碳水化合物消费情况来估计血糖指数和血糖负荷。研究的主要结果是主要心血管事件(心血管死亡、非致命性心肌梗死、中风和心力衰竭)或全因死亡。

随访期间,发生了8780例死亡以及8252例主要心血管事件。调整后,相比于血糖指数最低1/5人群,最高1/5人群的主要心血管事件及死亡风险显著增加,对于先前已经存在心血管疾病风险人群,其风险比为1.51,而先前未存在心血管疾病风险人群,其风险比为1.21,高血糖指数与心血管死亡风险增加相关。血糖负荷结果与血糖指数相似,但对于先前不存在心血管疾病风险因素的参与者,相关性并不显著。

研究认为,高血糖指数饮食增加心血管疾病及死亡风险

原始出处:                            

David J.A. Jenkins et al. Glycemic Index, Glycemic Load, and Cardiovascular Disease and Mortality. N Engl J Med, February 24 2021.

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    学习学习

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    2021-02-26 学医无涯

    糖尿病饮食对心血管有益

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1222001, encodeId=f022122200124, content=<a href='/topic/show?id=4f77e665253' target=_blank style='color:#2F92EE;'>#糖尿病#</a><a href='/topic/show?id=fc0f89831f0' target=_blank style='color:#2F92EE;'>#血糖指数#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76652, encryptionId=4f77e665253, topicName=糖尿病), TopicDto(id=89831, encryptionId=fc0f89831f0, topicName=血糖指数)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=清风徐来2022, createdTime=Tue May 24 11:16:34 CST 2022, time=2022-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2041015, encodeId=b0c72041015c9, content=<a href='/topic/show?id=6ef4898581e' target=_blank style='color:#2F92EE;'>#血糖负荷#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89858, encryptionId=6ef4898581e, topicName=血糖负荷)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Tue Jul 20 03:41:30 CST 2021, time=2021-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1837907, encodeId=5369183e9074a, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Tue Oct 26 22:41:30 CST 2021, time=2021-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=967052, encodeId=ff9796e05212, content=学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210705/53a490a287724bccb2fa931168d0dd76/bdc9f03d4b4343f89042ec03224e3ff4.jpg, createdBy=07b85416528, createdName=ms9000000254061880, createdTime=Wed May 19 21:11:48 CST 2021, time=2021-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1498834, encodeId=ab48149883469, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Sat Feb 27 10:41:30 CST 2021, time=2021-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=927282, encodeId=310392e28251, content=糖尿病饮食对心血管有益, beContent=null, objectType=article, channel=null, level=null, likeNumber=139, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b7a31928393, createdName=学医无涯, createdTime=Fri Feb 26 07:58:20 CST 2021, time=2021-02-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1035586, encodeId=f5ca103558689, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Feb 25 22:41:30 CST 2021, time=2021-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=927206, encodeId=2f4d92e2063b, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Thu Feb 25 19:57:52 CST 2021, time=2021-02-25, status=1, ipAttribution=)]
    2021-02-25 旺医

    顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1222001, encodeId=f022122200124, content=<a href='/topic/show?id=4f77e665253' target=_blank style='color:#2F92EE;'>#糖尿病#</a><a href='/topic/show?id=fc0f89831f0' target=_blank style='color:#2F92EE;'>#血糖指数#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76652, encryptionId=4f77e665253, topicName=糖尿病), TopicDto(id=89831, encryptionId=fc0f89831f0, topicName=血糖指数)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=清风徐来2022, createdTime=Tue May 24 11:16:34 CST 2022, time=2022-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2041015, encodeId=b0c72041015c9, content=<a href='/topic/show?id=6ef4898581e' target=_blank style='color:#2F92EE;'>#血糖负荷#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89858, encryptionId=6ef4898581e, topicName=血糖负荷)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Tue Jul 20 03:41:30 CST 2021, time=2021-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1837907, encodeId=5369183e9074a, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Tue Oct 26 22:41:30 CST 2021, time=2021-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=967052, encodeId=ff9796e05212, content=学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210705/53a490a287724bccb2fa931168d0dd76/bdc9f03d4b4343f89042ec03224e3ff4.jpg, createdBy=07b85416528, createdName=ms9000000254061880, createdTime=Wed May 19 21:11:48 CST 2021, time=2021-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1498834, encodeId=ab48149883469, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Sat Feb 27 10:41:30 CST 2021, time=2021-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=927282, encodeId=310392e28251, content=糖尿病饮食对心血管有益, beContent=null, objectType=article, channel=null, level=null, likeNumber=139, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b7a31928393, createdName=学医无涯, createdTime=Fri Feb 26 07:58:20 CST 2021, time=2021-02-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1035586, encodeId=f5ca103558689, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Feb 25 22:41:30 CST 2021, time=2021-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=927206, encodeId=2f4d92e2063b, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Thu Feb 25 19:57:52 CST 2021, time=2021-02-25, status=1, ipAttribution=)]
    2021-02-25 1209e435m98(暂无昵称)

    学习了,谢谢分享

    0

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