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Chest:高海拔儿童的过敏性鼻炎与阻塞性睡眠呼吸暂停

2019-10-05 xing.T MedSci原创

由此可见,在高海拔地区有症状的AR儿童中,AR严重程度增加与更严重的OSA有关。

阻塞性睡眠呼吸暂停(OSA)会影响2–4%的儿科人群;过敏性鼻炎(AR)已被确定为睡眠呼吸不良的危险因素,但此类关联尚未在高海拔环境中进行评估。近日,呼吸领域权威杂志chest上发表了一篇研究文章,研究人员旨在评估哥伦比亚波哥大高海拔城市接受多导睡眠监测(PSG)的儿童中AR的严重程度是否与OSA的严重程度有关。


研究人员进行了一项针对儿童AR的横断面观察研究。通过ESPRINT-15问卷和ARIA分类评估了AR严重程度,并使用PSG确定OSA的诊断和严重程度。研究人员应用二元logistic回归和Spearman相关系数(ρ)评估AR严重程度与OSA严重程度之间的潜在关联。


该研究共招募了99名儿童,平均年龄为7.9岁,女性占45%,53%患有OSA。ESPRINT-15评分与严重OSA相关(OR为2.0; 95%CI为1.12-6.04; P=0.01)。根据ARIA,中度/重度持续性鼻炎患者发生严重OSA的风险增加10.1倍(OR为10.15;95%CI为1.15 – 89.0)。此外,呼吸暂停低通气指数与ESPRINT-15评分(ρ=0.215; P=0.03)和ARIA严重程度评分(ρ=0.203; P=0.04)相关。 


由此可见,在高海拔地区有症状的AR儿童中,AR严重程度增加与更严重的OSA有关。  


原始出处:


Luis Fernando Giraldo-Cadavid,et al.Allergic Rhinitis and Obstructive Sleep Apnea in Children Residing at High-Altitude.chest.2019.https://journal.chestnet.org/article/S0012-3692(19)33947-9/fulltext


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    2020-03-19 tomyang96
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    2020-05-01 Smile2680
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  5. [GetPortalCommentsPageByObjectIdResponse(id=1696901, encodeId=e5861696901cc, content=<a href='/topic/show?id=d2e99e651e4' target=_blank style='color:#2F92EE;'>#阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97651, encryptionId=d2e99e651e4, topicName=阻塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23129903429, createdName=tomyang96, createdTime=Thu Mar 19 23:17:00 CST 2020, time=2020-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1929579, encodeId=80c819295e989, content=<a href='/topic/show?id=9e604625ab' target=_blank style='color:#2F92EE;'>#Chest#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4625, encryptionId=9e604625ab, topicName=Chest)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c48a270, createdName=Smile2680, createdTime=Fri May 01 14:17:00 CST 2020, time=2020-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2047167, encodeId=6359204e167bd, content=<a href='/topic/show?id=6f5294036b1' target=_blank style='color:#2F92EE;'>#过敏性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94036, encryptionId=6f5294036b1, topicName=过敏性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0a8e213, createdName=hongbochen, createdTime=Wed Aug 05 12:17:00 CST 2020, time=2020-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1989133, encodeId=1b14198913309, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Mon Mar 30 08:17:00 CST 2020, time=2020-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1942169, encodeId=30ed194216904, content=<a href='/topic/show?id=c489102465b4' target=_blank style='color:#2F92EE;'>#高海拔#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102465, encryptionId=c489102465b4, topicName=高海拔)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Fri Jan 10 19:17:00 CST 2020, time=2020-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1688388, encodeId=d24416883889b, content=<a href='/topic/show?id=df81656161b' target=_blank style='color:#2F92EE;'>#海拔#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65616, encryptionId=df81656161b, topicName=海拔)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f1c128575901, createdName=12498974m60暂无昵称, createdTime=Fri Nov 29 04:17:00 CST 2019, time=2019-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2051448, encodeId=7aab2051448af, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Sun Jul 05 14:17:00 CST 2020, time=2020-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1596577, encodeId=2cf915965e707, content=<a href='/topic/show?id=70e4396491a' target=_blank style='color:#2F92EE;'>#呼吸暂停#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39649, encryptionId=70e4396491a, topicName=呼吸暂停)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e2a518392360, createdName=119337463, createdTime=Mon Oct 07 02:17:00 CST 2019, time=2019-10-07, status=1, ipAttribution=)]
    2020-01-10 zsyan
  6. [GetPortalCommentsPageByObjectIdResponse(id=1696901, encodeId=e5861696901cc, content=<a href='/topic/show?id=d2e99e651e4' target=_blank style='color:#2F92EE;'>#阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97651, encryptionId=d2e99e651e4, topicName=阻塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23129903429, createdName=tomyang96, createdTime=Thu Mar 19 23:17:00 CST 2020, time=2020-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1929579, encodeId=80c819295e989, content=<a href='/topic/show?id=9e604625ab' target=_blank style='color:#2F92EE;'>#Chest#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4625, encryptionId=9e604625ab, topicName=Chest)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c48a270, createdName=Smile2680, createdTime=Fri May 01 14:17:00 CST 2020, time=2020-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2047167, encodeId=6359204e167bd, content=<a href='/topic/show?id=6f5294036b1' target=_blank style='color:#2F92EE;'>#过敏性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94036, encryptionId=6f5294036b1, topicName=过敏性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0a8e213, createdName=hongbochen, createdTime=Wed Aug 05 12:17:00 CST 2020, time=2020-08-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1989133, encodeId=1b14198913309, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Mon Mar 30 08:17:00 CST 2020, time=2020-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1942169, encodeId=30ed194216904, content=<a href='/topic/show?id=c489102465b4' target=_blank style='color:#2F92EE;'>#高海拔#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102465, encryptionId=c489102465b4, topicName=高海拔)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Fri Jan 10 19:17:00 CST 2020, time=2020-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1688388, encodeId=d24416883889b, content=<a href='/topic/show?id=df81656161b' target=_blank style='color:#2F92EE;'>#海拔#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65616, encryptionId=df81656161b, topicName=海拔)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f1c128575901, createdName=12498974m60暂无昵称, createdTime=Fri Nov 29 04:17:00 CST 2019, time=2019-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2051448, encodeId=7aab2051448af, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Sun Jul 05 14:17:00 CST 2020, time=2020-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1596577, encodeId=2cf915965e707, content=<a href='/topic/show?id=70e4396491a' target=_blank style='color:#2F92EE;'>#呼吸暂停#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39649, encryptionId=70e4396491a, topicName=呼吸暂停)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e2a518392360, createdName=119337463, createdTime=Mon Oct 07 02:17:00 CST 2019, time=2019-10-07, status=1, ipAttribution=)]
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