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肥胖患者结肠癌根治全麻术中严重低氧血症一例

2017-11-26 佚名 临床麻醉学杂志

患者,男,61岁,175cm,110kg,因“下消化道治疗术后半月,发现结肠癌1周余”入院

【一般资料】

患者,男,61岁,175cm,110kg

【主诉】

因“下消化道治疗术后半月,发现结肠癌1周余”入院

【现病史】

患者半月前因“消化道出血”入住当地医院消化科,并行结肠镜检查示“结肠(肝曲)癌”,为进一步手术治疗,收住我院。

【既往史】

患者既往高血压、冠心病史,2月前因“心肌梗死”于当地医院行冠脉支架植入术,术后口服拜阿司匹林肠溶片、替格瑞洛。

【初步诊断

初步诊断为“结肠癌、冠状动脉支架植入术后、高血压病、冠状动脉粥样硬化性心脏病”,术前肺功能检查示“轻度限制性通气功能障碍,峰流速正常,弥散功能降低,残/总比例降低”心电图检查示“窦性心律,陈旧性下壁、前壁心肌梗死,完全性右束支传导阻滞”。

【治疗】

拟择期在静-吸复合全身麻醉下行“右半结肠切除术”。患者于术前30min肌注苯巴比妥钠0.1mg、阿托品0.5mg。入室后监测,HR85次/分,BP160/80mmHg,SpO292%。麻醉诱导:咪达唑仑2mg、维库溴铵8mg、舒芬太尼30μg、丙泊酚120mg、甲基强的松龙80mg。纤维支气管镜定位气管插管,接呼吸机控制通气,设置呼吸机参数:VT600ml,RR12次/分,I∶E1∶2,PETCO223~25mmHg。麻醉维持:瑞芬太尼和丙泊酚静脉持续泵注,七氟醚吸入维持,间断推注维库溴铵维持肌松。术中持续监测有创动脉血压、中心静脉压。手术开始30min,SpO2跌至88%,HR80次/分,BP120/70mmHg,紧急查动脉血气分析示:pH7.4,PCO244mmHg,PO244mmHg,Lac1.0mmol/L,BE2.1mmol/L,HCO3-26mmol/L,THbc125g/L。紧急请呼吸科、心内科会诊,急查BNP、急诊DIC、DD-二聚体、生化全套,数值均在正常范围内,重新设置呼吸机参数,RR15次/分,增加PEEP7cmH2O,30min后查血气分析示:pH7.37,PCO247mmHg,PO249mmHg,Lac1.3mmol/L,BE1.4mmol/L,HCO-327.2mmol/L,THbc122g/L,SpO2持续88%。BP一直波动于120/70mmHg、HR80次/分左右,听诊双肺底未闻及明显干湿啰音。手术仍持续进行。30min后SpO2升至92%,查动脉血气分析示:pH7.39,PCO243mmHg,PO255mmHg,Lac1.3mmol/L,BE0.8mmol/L,HCO-326mmol/L,THbc125g/L。手术结束,恢复自主呼吸后,吸纯氧情况下SpO2升至96%。患者带气管插管转到ICU。第2天拔除气管导管返回普通病房。

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  5. [GetPortalCommentsPageByObjectIdResponse(id=1950983, encodeId=35c01950983fc, content=<a href='/topic/show?id=72078190803' target=_blank style='color:#2F92EE;'>#肥胖患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81908, encryptionId=72078190803, topicName=肥胖患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28b7142, createdName=liuquan, createdTime=Wed Feb 21 23:07:00 CST 2018, time=2018-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2040531, encodeId=dd792040531ce, content=<a href='/topic/show?id=8d9229e76af' target=_blank style='color:#2F92EE;'>#全麻术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29776, encryptionId=8d9229e76af, topicName=全麻术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Wed May 30 21:07:00 CST 2018, time=2018-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1377317, encodeId=39a513e7317e3, content=<a href='/topic/show?id=1d4c26235f1' target=_blank style='color:#2F92EE;'>#低氧血症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26235, encryptionId=1d4c26235f1, topicName=低氧血症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=279b407, createdName=shanyongle, createdTime=Tue Nov 28 01:07:00 CST 2017, time=2017-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1476559, encodeId=dcf014e655965, content=<a href='/topic/show?id=6ff229e7126' target=_blank style='color:#2F92EE;'>#全麻#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29771, encryptionId=6ff229e7126, topicName=全麻)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Tue Nov 28 01:07:00 CST 2017, time=2017-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1586083, encodeId=9cdf158608394, content=<a href='/topic/show?id=38f8622191b' target=_blank style='color:#2F92EE;'>#根治#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62219, encryptionId=38f8622191b, topicName=根治)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26d917348678, createdName=jeanqiuqiu, createdTime=Tue Nov 28 01:07:00 CST 2017, time=2017-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264863, encodeId=5c862648638e, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Mon Nov 27 22:02:28 CST 2017, time=2017-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264697, encodeId=997326469ec4, content=学习了.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Mon Nov 27 09:33:39 CST 2017, time=2017-11-27, status=1, ipAttribution=)]
    2017-11-28 jeanqiuqiu
  6. [GetPortalCommentsPageByObjectIdResponse(id=1950983, encodeId=35c01950983fc, content=<a href='/topic/show?id=72078190803' target=_blank style='color:#2F92EE;'>#肥胖患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81908, encryptionId=72078190803, topicName=肥胖患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28b7142, createdName=liuquan, createdTime=Wed Feb 21 23:07:00 CST 2018, time=2018-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2040531, encodeId=dd792040531ce, content=<a href='/topic/show?id=8d9229e76af' target=_blank style='color:#2F92EE;'>#全麻术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29776, encryptionId=8d9229e76af, topicName=全麻术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Wed May 30 21:07:00 CST 2018, time=2018-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1377317, encodeId=39a513e7317e3, content=<a href='/topic/show?id=1d4c26235f1' target=_blank style='color:#2F92EE;'>#低氧血症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26235, encryptionId=1d4c26235f1, topicName=低氧血症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=279b407, createdName=shanyongle, createdTime=Tue Nov 28 01:07:00 CST 2017, time=2017-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1476559, encodeId=dcf014e655965, content=<a href='/topic/show?id=6ff229e7126' target=_blank style='color:#2F92EE;'>#全麻#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29771, encryptionId=6ff229e7126, topicName=全麻)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Tue Nov 28 01:07:00 CST 2017, time=2017-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1586083, encodeId=9cdf158608394, content=<a href='/topic/show?id=38f8622191b' target=_blank style='color:#2F92EE;'>#根治#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62219, encryptionId=38f8622191b, topicName=根治)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26d917348678, createdName=jeanqiuqiu, createdTime=Tue Nov 28 01:07:00 CST 2017, time=2017-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264863, encodeId=5c862648638e, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Mon Nov 27 22:02:28 CST 2017, time=2017-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264697, encodeId=997326469ec4, content=学习了.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Mon Nov 27 09:33:39 CST 2017, time=2017-11-27, status=1, ipAttribution=)]
    2017-11-27 smartxiuxiu

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1950983, encodeId=35c01950983fc, content=<a href='/topic/show?id=72078190803' target=_blank style='color:#2F92EE;'>#肥胖患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81908, encryptionId=72078190803, topicName=肥胖患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28b7142, createdName=liuquan, createdTime=Wed Feb 21 23:07:00 CST 2018, time=2018-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2040531, encodeId=dd792040531ce, content=<a href='/topic/show?id=8d9229e76af' target=_blank style='color:#2F92EE;'>#全麻术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29776, encryptionId=8d9229e76af, topicName=全麻术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Wed May 30 21:07:00 CST 2018, time=2018-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1377317, encodeId=39a513e7317e3, content=<a href='/topic/show?id=1d4c26235f1' target=_blank style='color:#2F92EE;'>#低氧血症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26235, encryptionId=1d4c26235f1, topicName=低氧血症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=279b407, createdName=shanyongle, createdTime=Tue Nov 28 01:07:00 CST 2017, time=2017-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1476559, encodeId=dcf014e655965, content=<a href='/topic/show?id=6ff229e7126' target=_blank style='color:#2F92EE;'>#全麻#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29771, encryptionId=6ff229e7126, topicName=全麻)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Tue Nov 28 01:07:00 CST 2017, time=2017-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1586083, encodeId=9cdf158608394, content=<a href='/topic/show?id=38f8622191b' target=_blank style='color:#2F92EE;'>#根治#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62219, encryptionId=38f8622191b, topicName=根治)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26d917348678, createdName=jeanqiuqiu, createdTime=Tue Nov 28 01:07:00 CST 2017, time=2017-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264863, encodeId=5c862648638e, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Mon Nov 27 22:02:28 CST 2017, time=2017-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264697, encodeId=997326469ec4, content=学习了.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Mon Nov 27 09:33:39 CST 2017, time=2017-11-27, status=1, ipAttribution=)]
    2017-11-27 明天会更好!

    学习了.谢谢分享!

    0

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