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Diabetes Care:妊娠糖尿病与心衰的关系

2021-08-19 MedSci原创 MedSci原创

在这项大型观察性研究中,GDM与HF风险增加相关。因此,建议在妊娠期间进行糖尿病筛查以识别具有HF风险的女性。

近日,糖尿病领域权威杂志Diabetes Care上发表了一篇研究文章,该研究旨在评估妊娠期糖尿病(GDM)是否与心力衰竭(HF)风险增加相关。


研究人员使用安大略省(加拿大)卫生保健管理数据库中的信息进行了一项基于人群的队列研究,确定了安大略省所有在2007年7月1日至2018年3月31日期间单胎活产的GDM女性。

该研究排除了妊娠前患有糖尿病或心衰的女性。GDM是根据实验室检查结果和诊断代码进行定义。该研究的主要结局是从首次妊娠到2019年3月31日期间发生的心衰住院,次要结局是首次妊娠时发生的围产期心肌病。研究人员针对相关的心脏代谢危险因素调整了相关性估计值。


在906319名符合条件的女性(平均年龄为30岁[SD为5.6],50193名[5.5%]GDM患者)中,中位随访7年期间发生了763起HF事件。与无GDM相比,GDM与更高的HF风险相关(调整后的风险比[aHR]为1.62[95%CI为1.28,2.05])。在考虑了慢性肾病、产后糖尿病、高血压和冠状动脉疾病后,这种关联仍然显著(aHR为1.39[95%CI为1.09,1.79])。GDM增加了围产期心肌病的发生几率(调整后的比值比为1.83[95%CI为1.45,2.33])。
 
由此可见,在这项大型观察性研究中,GDM与HF风险增加相关。因此,建议在妊娠期间进行糖尿病筛查以识别具有HF风险的女性
 
原始出处:
 
Justin B. Echouffo-Tcheugui,et al.Gestational Diabetes and Incident Heart Failure: A Cohort Study.Diabetes care.2021.https://care.diabetesjournals.org/content/early/2021/08/12/dc21-0552

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    2021-12-14 D-House

    学习啦

    0

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    2021-11-08 小雨闲

    学习

    0

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    2021-09-14 病毒猎手

    #妊娠糖尿病##心衰#挂上钩,是最新的热点领域了

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1902606, encodeId=7f2d190260658, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Wed Sep 01 03:59:44 CST 2021, time=2021-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1639846, encodeId=19af163984608, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sat Sep 04 14:59:44 CST 2021, time=2021-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1080025, encodeId=98df10800250f, content=学习啦, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220625/6f4f075937de4c5d9fc7ab3a1bc6d8c2/13a8a29e67044698af1fb74276589093.jpg, createdBy=b5c55099112, createdName=D-House, createdTime=Tue Dec 14 17:51:18 CST 2021, time=2021-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1068253, encodeId=82311068253d5, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=10b65509612, createdName=小雨闲, createdTime=Mon Nov 08 20:41:46 CST 2021, time=2021-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1051100, encodeId=2a48105110080, content=<a href='/topic/show?id=27b94491893' target=_blank style='color:#2F92EE;'>#妊娠糖尿病#</a>与<a href='/topic/show?id=f5cb5192610' target=_blank style='color:#2F92EE;'>#心衰#</a>挂上钩,是最新的热点领域了, beContent=null, objectType=article, channel=null, level=null, likeNumber=167, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44918, encryptionId=27b94491893, topicName=妊娠糖尿病), TopicDto(id=51926, encryptionId=f5cb5192610, topicName=心衰)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211210/ede9c51184aa4f54ae6c1164cfb8eeac/967dbf3eff2943c7bf3ccfec3a776ab0.JPG, createdBy=a33789389, createdName=病毒猎手, createdTime=Tue Sep 14 13:51:59 CST 2021, time=2021-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1761659, encodeId=8f9f1e61659ab, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Thu Apr 07 06:59:44 CST 2022, time=2022-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1043746, encodeId=03531043e4674, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Thu Aug 19 20:59:44 CST 2021, time=2021-08-19, status=1, ipAttribution=)]
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    2021-08-19 misszhang

    谢谢MedSci提供最新的资讯

    0

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